ALEXIS Biochemicals: Ciglitazone

ALX-270-255

Revised 14-Sep-07

Ciglitazone
SYNONYMS	(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione U-63287
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	PPAR Agonists

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-255-M001		1 mg	30.00 USD
ALX-270-255-M005		5 mg	80.00 USD
ALX-270-255-M025		25 mg	310.00 USD

Product Specification

FORMULA:	C₁₈H₂₃NO₃S
MW:	333.5
CAS NUMBER:	74772-77-3
SOURCE/HOST:	Synthetic.
PURITY:	≥98%
APPEARANCE:	Off-white solid.
SOLUBILITY:	Soluble in DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
USE/STABILITY:	Stock solutions are stable for up to 3 months when stored at -20°C.

Product Description

Selective PPARγ agonist.

Product Specific Literature References

The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones: T.M. Willson, et al.; J. Med. Chem. 39, 665 (1996) Abstract; Full Text
Detection and functional characterisation of the transcription factor peroxisome proliferator-activated receptor gamma in lutein cells: B. Löhrke, et al.; J. Endocrinol. 159, 429 (1998) Abstract; Full Text
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo: X. Xin, et al.; J. Biol. Chem. 274, 9116 (1999) Abstract; Full Text
Thiazolidinediones--the new insulin enhancers: R.J. Jha; Clin. Exp. Hypertens. 21, 157 (1999), (Review) Abstract
The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses: R.B. Clark, et al.; J. Immunol. 164, 1364 (2000) Abstract; Full Text

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