ALEXIS Biochemicals: Cinobufotalin

ALX-350-284

Revised 11-Jun-07

Cinobufotalin
SYNONYMS	14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - ATPase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-284-M005		5 mg	85.00 USD

Product Specification

FORMULA:	C₂₆H₃₄O₇
MW:	458.6
CAS NUMBER:	1108-68-5
MERCK INDEX:	14: 2307
PURITY:	≥99%
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
HAZARD:	TOXIC.

Product Description

Specific Na⁺/K⁺-ATPase inhibitor. Less active than ouabain (Prod. No. ALX-350-066).

Product Specific Literature References

Actions of bufalin and cinobufotalin, two bufadienolides respectively more active and less active than ouabain, on ouabain binding and 86Rb uptake by human erythrocytes: A.A. Brownlee, et al.; Clin. Sci. (Lond.) 78, 169 (1990) Abstract
Neutralization of cardiac toxins oleandrin, oleandrigenin, bufalin, and cinobufotalin by digibind: monitoring the effect by measuring free digitoxin concentrations: A. Dasgupta & L. Emerson ; Life Sci. 63, 781 (1998) Abstract
Simultaneous determination of four bufadienolides in human liver by high-performance liquid chromatography: Z. Wang, et al.; Biomed. Chromatogr. 18, 318 (2004) Abstract
Cardiotonic steroids differentially affect intracellular Na+ and [Na+]i/[K+]i-independent signaling in C7-MDCK cells: O.A. Akimova, et al.; J. Biol. Chem. 280, 832 (2005) Abstract

Further Categories Containing This Product:

Na+/K+-ATPase/Related Products • Natural Products - Immunomodulators

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