ALEXIS Biochemicals: Ciprofibrate

ALX-270-475

Revised 17-Jan-08

Ciprofibrate
SYNONYMS	2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
PRODUCT LINE	Obesity & Adipokines
PRODUCT CATEGORY	Cholesterol & Lipid Transport/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-475-M025		25 mg	50.00 USD
ALX-270-475-M100		100 mg	150.00 USD
ALX-270-475-M250		250 mg	300.00 USD

Product Specification

FORMULA:	C₁₃H₁₄Cl₂O₃
MW:	289.2
CAS NUMBER:	52214-84-3
MERCK INDEX:	14: 2313
RTECS:	UF0880000
PURITY:	≥98% (HPLC)
APPEARANCE:	White to light yellow powder.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	TOXIC. MAY BE CARCINOGENIC.

Product Description

Hypolipidemic compound. PPARα (peroxisome proliferator-activated receptor α) agonist.

Product Specific Literature References

Comparison of the effects of various peroxisome proliferators on peroxisomal enzyme activities, DNA synthesis, and apoptosis in rat and human hepatocyte cultures: V. Goll, et al.; Toxicol. Appl. Pharmacol. 160, 21 (1999) Abstract
Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate: P. Passilly, et al.; Biochem. Pharmacol. 58, 1001 (1999) Abstract
Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate: M.C. Clemencet, et al.; Cancer Lett. 222, 217 (2005) Abstract
P450 CYP2C epoxygenase and CYP4A ω-hydroxylase mediate ciprofibrate-induced PPARα-dependent peroxisomal proliferation: A. Gatica, et al.; J. Lipid Res. 48, 924 (2007) Abstract; Full Text

ALX-270-256	Clofibrate
ALX-270-481	Fenofibrate