ALEXIS Biochemicals: Colistin . sulfate

ALX-380-272

Revised 14-Feb-08

Colistin . sulfate
SYNONYMS	Polymyxin E . sulfate
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-272-M500		500 mg	85.00 USD

Product Specification

CAS NUMBER:	1264-72-8
MERCK INDEX:	14: 2479
RTECS:	TR1500000
SOURCE/HOST:	Isolated from Bacillus colistinus.
APPEARANCE:	White to off-white powder.
PURITY DETAIL:	Mixture of >30 compounds, primarily colistin A and B.
SOLUBILITY:	Soluble in water (50mg/ml).
ACTIVITY:	Potency is >19’900µg/ml (on dry basis).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	TOXIC.
Colistin B

Product Description

Polymyxin antibiotic. Binds to lipids on the cell cytoplasmic membrane. Disrupts cell wall integrity. Effective against Gram-negative bacteria.

Product Specific Literature References

Antibacterial action of colistin (polymyxin E) against Mycobacterium aurum: H.L. David & N. Rastogi; Antimicrob. Agents Chemother. 27, 701 (1985) Abstract; Full Text
Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram-negative bacteria: M.E. Evans, et al.; Ann. Pharmacother. 33, 960 (1999), (Review) Abstract
The clinical use of colistin in patients with cystic fibrosis: P. Beringer; Curr. Opin. Pulm. Med. 7, 434 (2001), (Review) Abstract

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