ALEXIS Biochemicals: Compound 15e

ALX-270-455

Revised 18-Dec-06

Compound 15e
SYNONYMS	3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Phosphoinositide 3-kinase [PI(3)K]/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-455-M001		1 mg	50.00 USD
ALX-270-455-M005		5 mg	190.00 USD

Product Specification

FORMULA:	C₁₆H₁₅N₃O₂S
MW:	313.4
CAS NUMBER:	371943-05-4
PURITY:	≥99% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO or dioxane.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Potent and specific inhibitor of phosphoinositide 3-kinase p110α isoform. Inhibits proliferation of A375 melanoma cells (IC₅₀=0.58µM).

Product Specific Literature References

Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors: M. Hayakawa, et al.; Bioorg. Med. Chem. 14, 6847 (2006) Abstract

Further Categories Containing This Product:

Antitumor Agents (Anti-proliferative)

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