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ALX-270-248 Revised 17-Jul-07
Compound 52
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SYNONYMS 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY CDK & Cyclin Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-248-M001   1 mg 55.00 USD Add To Cart
Product Specification
FORMULA: C16H19ClN6O
MW: 346.8
PURITY: ≥99%
APPEARANCE: Off-white solid.
SOLUBILITY: Soluble in DMSO or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Potent, cell permeable and selective inhibitor of CDK1 (IC50=340nM) the cell cycle-regulating kinase Cdc28p (IC50=7µM) and the related Pho85p kinase (IC50=2µM).
Product Specific Literature References
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors: N.S. Gray, et al.; Science 281, 533 (1998) Abstract
 
 
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