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ALX-380-225 Revised 15-Feb-08
Conglobatin
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Antibiotics - Immunomodulators
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-380-225-MC05   0.5 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C28H38N2O6
MW: 498.6
CAS NUMBER: 72263-05-9
RTECS: JG7521800
SOURCE/HOST: Isolated from Streptomyces conglobatus MST-AS5530.
PURITY: ≥95% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: HARMFUL.

Product Description
Macrolide antibiotic with an unusual dimeric macrolide dilactone structure. Exhibited immunosuppressant activity in a NFAT-dependent transcription assay (IC50=0.63µg/ml).
Product Specific Literature References
Conglobatin, a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005: J.W. Westley, et al.; J. Antibiot. (Tokyo) 32, 874 (1979) Abstract
Simple aromatics identified with a NFAT-lacZ transcription assay for the detection of immunosuppressants: N.S. Burres, et al.; J. Antibiot. (Tokyo) 48, 380 (1995) Abstract
 
 
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