ALEXIS Biochemicals: Cyclin-dependent Kinase 2 Inhibitory Peptide II

ALX-153-042

Revised 04-Mar-05

Cyclin-dependent Kinase 2 Inhibitory Peptide II
SYNONYMS	CDK2/Cyclin Inhibitory Peptide II
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	CDK & Cyclin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-153-042-C500		500 µg	145.00 USD

Product Specification

SEQUENCE:	H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Asp-Leu-OH
FORMULA:	C₁₁₀H₂₀₀N₄₈O₂₅
MW:	2595.1
PURITY:	≥98%
APPEARANCE:	Lyophilized solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Very hygroscopic.

Product Description

Cell permeable inhibitor of CDK2/cyclin complexes. Blocks phosphorylation of substrates by CDK2/cyclin A and CDK/cyclin E complexes. Preferentially induces apoptosis only in transformed cells and not in non-transformed cells.

Product Specific Literature References

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists: Y.N. Chen, et al.; PNAS 96, 4325 (1999) Abstract; Full Text

Further Categories Containing This Product:

Peptides • Apoptosis Inducers & Inhibitors Other Products

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