ALEXIS Biochemicals: Cytochalasin A

ALX-380-057

Revised 03-Apr-08

Cytochalasin A
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics for Cytoskeletal Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-057-M001		1 mg	50.00 USD
ALX-380-057-M005		5 mg	170.00 USD
ALX-380-057-M010		10 mg	290.00 USD

Product Specification

FORMULA:	C₂₉H₃₅NO₅
MW:	477.6
CAS NUMBER:	14110-64-6
MERCK INDEX:	14: 2790
SOURCE/HOST:	Isolated from Helminthosporium dematioideum.
PURITY:	≥98% (HPLC)
APPEARANCE:	White powder.
SOLUBILITY:	Soluble in acetone, DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
HAZARD:	TOXIC.

Product Description

Antibiotic. Fungal toxin. Inhibits glucose transport, actin polymerisation and blocks the formation of microtubuli. Inhibits cell division. Inhibits HIV-1 protease.

Product Specific Literature References

The action of cytochalasin A on the in vitro polymerization of brain tubulin and muscle G-actin: R.H. Himes & L.L. Houston; J. Supramol. Struct. 5, 81 (1976) Abstract
Cytochalasin A inhibits B-lymphocyte capping and activation by antigens: G. Teti, et al.; Immunol. Lett. 3, 151 (1981) Abstract
L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. III. Biological activity: R.B. Lingham, et al.; J. Antibiot. 45, 686 (1992) Abstract
Effect of cytochalasin A on apical growth, actin cytoskeleton organization and enzyme secretion in Aspergillus nidulans: S. Torralba, et al.; Microbiology 144 (Pt 1), 45 (1998) Abstract

Further Categories Containing This Product:

Microtubule Modulators • Alkaloids • Mycotoxins

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