ALEXIS Biochemicals: D-myo-Inositol 3,4,5,6-tetrakisphosphate . octasodium salt

ALX-307-061

Revised 14-Feb-06

D-myo-Inositol 3,4,5,6-tetrakisphosphate . octasodium salt
SYNONYMS	Ins(3,4,5,6)P₄ . 8Na
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Inositols & Inositolphosphates/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-307-061-C100		100 µg	160.00 USD
ALX-307-061-M001		1 mg	760.00 USD

Product Specification

FORMULA:	C₆H₈O₁₈P₄ . 8Na
MW:	492.0 . 183.9
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Hygroscopic.
IDENTITY:	Identity determined by ¹H-NMR, ³¹P-NMR and MS.

Product Description

Uncouples chloride secretion from the Ca²⁺ signal. Reduces Cl^- secretion.

Product Specific Literature References

Long-term uncoupling of chloride secretion from intracellular calcium levels by Ins(3,4,5,6)P4: M. Vajanaphanich, et al.; Nature 371, 711 (1994) Abstract
myo-inositol 3,4,5,6-tetrakisphosphate inhibits an apical calcium-activated chloride conductance in polarized monolayers of a cystic fibrosis cell line: M.A. Carew, et al.; J. Biol. Chem. 275, 26906 (2000) Abstract; Full Text

General Information

MANUFACTURER

Manufactured by SiChem, Germany.

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