ALEXIS Biochemicals: DCC (Fibronectin Domain 5) (human) (recombinant)

ALX-522-109

Revised 14-Apr-08

DCC (Fibronectin Domain 5) (human) (recombinant)
SYNONYMS	Deleted in Colorectal Cancer Protein (Fibronectin Domain 5) (human) (recombinant)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Netrins & Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-522-109-C050		50 µg	360.00 USD

Product Specification

SOURCE/HOST:	Produced in E. coli. The fibronectin domain 5 (FBN5) of human DCC (aa 841-941) is fused to a N-terminal tag.
CONCENTRATION:	1mg/ml after reconstitution.
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Lyophilized. Contains PBS.
ENDOTOXIN CONTENT:	<0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION:	Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY:	Binds to human netrin-1.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

Product Specific Literature References

Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer: J. Fitamant, et al.; PNAS 105, 4850 (2008) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION	Swiss-Prot link Q16218: Deleted in Colorectal Cancer Protein (human)
MANUFACTURER	Manufactured by Apotech Corporation.

General Literature References

Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin: B.V. Geisbrecht, et al.; J. Biol. Chem. 278, 32561 (2003) Abstract

Further Categories Containing This Product:

Recombinant Proteins / Fusion Proteins • Fibronectin / Related Products

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