ALEXIS Biochemicals: DL-AP5

ALX-550-034

Revised 25-Jul-08

DL-AP5
SYNONYMS	DL-2-Amino-5-phosphonopentanoic acid
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	NMDA Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-034-M005		5 mg	30.00 USD
ALX-550-034-M025		25 mg	120.00 USD

Product Specification

FORMULA:	C₅H₁₂NO₅P
MW:	197.1
CAS NUMBER:	76326-31-3
PURITY:	≥97% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in 1M NaOH or water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from light.
IDENTITY:	Identity determined by ¹H-NMR.

Product Description

Potent and selective NMDA receptor antagonist.

Product Specific Literature References

2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation: J. Davies, et al.; Neurosci. Lett. 21, 77 (1981) Abstract
Excitatory amino acid transmitters: J.C. Watkins and R.H. Evans; Ann. Rev. Pharmacol. Toxicol. 21, 165 (1981), (Review) Abstract
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations: R.H. Evans, et al.; Br. J. Pharmacol. 75, 65 (1982) Abstract
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4- phosphonobutyrate in the cat spinal cord: J. Davies and J.C. Watkins; Brain Res. 235, 378 (1982) Abstract

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