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ALX-210-152/1
Revised 28-Feb-08
Polyclonal Antibody to Androgen Receptor
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Androgens & Androgen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-152/1-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope affinity-purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to N-terminal aa 1-21 (M
1
EVQLGLGRVYPRPPSKTYRG
21
C) of human, mouse and rat androgen receptor.
SPECIFICITY:
Recognizes human androgen receptor. Detects a band of ~110kDa by Western blot. Does not cross-react with estrogen, progesterone, or glucocorticoid receptors.
APPLICATION:
Western Blot (2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-151-033
.
Product Specific Literature References
Immunocytochemical analysis of androgen receptor along the ducts of the separate rat prostate lobes after androgen withdrawal and replacement:
G.S. Prins, et al.; Endocrinology
132
, 169 (1993)
Abstract
Androgen receptor localization in different cell types of the adult rat prostate:
G.S. Prins, et al.; Endocrinology
129
, 3187 (1991)
Abstract
Related Products
ALX-151-033
Blocking Peptide for PAb to Androgen Receptor (Prod. No.
ALX-210-152/1
)
Further Categories Containing This Product:
Polyclonal Antibodies
•
Tumor Markers
ALX-210-201
Revised 22-May-06
Polyclonal Antibody to Estrogen Receptor α
SYNONYMS
anti-ERα PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Estrogen & Estrogen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-201-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-21 (M
1
TMTLHTKASGMALLHQIQGN
21
) of N-terminal human ERα (estrogen receptor α). This sequence is completely conserved in rat and mouse ERα and is highly conserved in sheep, pig, dog, bovine and chicken ERα.
SPECIFICITY:
Recognizes human and rat endogenous ERα . Detects a band of ~64kDa by Western blot. Does not cross-react with ERβ.
APPLICATION:
Immunocytochemistry
Immunohistochemistry (frozen sections, paraffin sections (1-5µg/ml))
Western Blot (1µg/ml).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-155-031
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Differential Regulation of Estrogen Receptor Subtypes alpha and beta in Human Aortic Smooth Muscle Cells by Oligonucleotides and Estradiol:
F. Barchiesi, et al.; J. Clin. Endocrinol. Metab.
89
, 2373 (2004)
Abstract
Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast:
R.K. Dubey, et al.; J. Clin. Endocrinol. Metab.
90
, 247 (2005)
Abstract
;
Full Text
Related Products
ALX-155-031
Blocking Peptide for PAb to Estrogen Receptor α (Prod. No.
ALX-210-201
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-202
Revised 20-Dec-07
Polyclonal Antibody to Estrogen Receptor α
SYNONYMS
anti-ERα PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Estrogen & Estrogen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-202-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
Pig
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
FORMULATION:
Liquid. Epitope-affinity purified IgG in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 21-32 (N
21
ELEPLNRPQLK
32
) of N-terminal human ERα (estrogen receptor α). This sequence is completely conserved in mouse, rat, rabbit, sheep, pig and bovine ERα.
SPECIFICITY:
Recognizes human, rat and pig endogenous ERα. Detects a band of ~64kDa by Western blot. Does not cross-react with ERβ.
APPLICATION:
Immunocytochemistry (0.5µg/ml)
Immunohistochemistry (frozen sections, paraffin sections (1-5µg/ml))
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-155-032
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-155-032
Blocking Peptide for PAb to Estrogen Receptor α (Prod. No.
ALX-210-202
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-132
Revised 07-Jan-08
Polyclonal Antibody to Estrogen Receptor β
SYNONYMS
anti-ERβ PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Estrogen & Estrogen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-132-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope-affinity purified.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 512-530 (C
512
SSTEDSKN KESSQNLQSQ
530
) of C-terminal rat ERβ (estrogen receptor β
).
SPECIFICITY:
Recognizes human, mouse and rat ERβ.
Detects a band of ~55kDa by Western blot. Does not
cross-react with ERα.
APPLICATION:
Immunocytochemistry (1µg/ml)
Immunohistochemistry ((paraffin sections, frozen sections (1:50))
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-155-025
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Transcription and translation of estrogen receptor-beta in the male reproductive tract of estrogen receptor-alpha knock-out and wild-type mice:
C.S. Rosenfeld, et al.; Endocrinology
139
, 2982 (1998)
Abstract
Generation and reproductive phenotypes of mice lacking estrogen receptor beta:
J.H. Krege, et al.; PNAS
95
, 15677 (1998)
Abstract
;
Full Text
Distribution of estrogen-beta-like immunoreactivity in rat forebrain:
X. Li, et al.; Neuroendocrinology
66
, 63 (1997)
Abstract
Related Products
ALX-155-025
Blocking Peptide for PAb to Estrogen Receptor β (Prod. No.
ALX-210-132
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-135
Revised 21-May-08
Polyclonal Antibody to Estrogen Receptor β
SYNONYMS
anti-ERβ PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Estrogen & Estrogen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-135-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
Others
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 100-115 (A
100
EPQKSPWCEARSLEH
115
) of human, mouse and rat ERβ (estrogen receptor β).
SPECIFICITY:
Recognizes human, mouse, rat, sheep and monkey ERβ. Detects a band of ~55kDa by Western blot. Does not cross-react with ERα.
APPLICATION:
Gel Shift Assay (1-5µg/ml)
Immunocytochemistry (2-4µg/ml))
Immunohistochemistry ((frozen sections, paraffin sections (1-2µg/ml))
Western Blot (1-2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-155-027
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Cloning of a novel receptor expressed in rat prostate and ovary:
G.G.J.H. Kuiper, et al.; PNAS
93
, 5925 (1996)
Abstract
ER beta: identification and characterization of a novel human estrogen receptor:
S. Mosselman, et al.; FEBS Lett.
392
, 49 (1996)
Abstract
Transcription and translation of estrogen receptor b in the male reproductive tract of estrogen receptor a-knock-out and wild-type mice:
C.S. Rosenfeld, et al.; Endocrinology
139
, 2982 (1998)
Abstract
Differing roles found for estrogen's two receptors:
E. Pennisi; Science
277
, 1439 (1997), (Research News)
Abstract
Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta:
G.B. Tremblay, et al.; Mol. Endocrinol.
11
, 353 (1997)
Abstract
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta:
G.G.J.H. Kuiper, et al.; Endocrinology
138
, 863 (1997)
Abstract
Distribution of estrogen receptor-beta-like immunoreactivity in rat forebrain:
X. Li, et al.; Neuroendocrinology
66
, 63 (1997)
Abstract
A new actor in the estrogen receptor drama--enter ER-beta:
B.S. Katzenellenbogen & K.S. Korach; Endocrinology
138
, 861 (1997), (Editorial)
Abstract
Related Products
ALX-155-027
Blocking Peptide for PAb to Estrogen Receptor β (Prod. No.
ALX-210-135
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-178
Revised 11-Nov-05
Polyclonal Antibody to Estrogen Receptor β
SYNONYMS
anti-ERβ PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Estrogen & Estrogen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-178-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Epitope affinity purified IgG in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 512-530(C
512
CSTEDSKSKEGSQNLQSQ
530
) of C-terminal mouse ERβ (estrogen receptor β
).
SPECIFICITY:
Recognizes human and rat ERβ.
D
etects a band of ~55kDa by Western blot. Does not cross-react with ERα.
APPLICATION:
Immunohistochemistry (frozen sections (1-2µg/ml), paraffin sections (1-2µg/ml))
Western Blot (2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-155-030
.
Related Products
ALX-155-030
Blocking Peptide for PAb to Estrogen Receptor β (Prod. No.
ALX-210-178
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-180
Revised 21-Dec-06
Polyclonal Antibody to Estrogen Receptor β
SYNONYMS
anti-ERβ PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Estrogen & Estrogen Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-180-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 512-530(C
512
SPAEDSKSK
EGSQNPQSQ
530
) of C-terminal human ERβ (estrogen receptor β
).
SPECIFICITY:
Recognizes human and rat ERβ. Detects a band of ~55kDa by Western blot. Does not cross-react with ERα.
APPLICATION:
Immunohistochemistry (frozen sections (2-5µg/ml), paraffin sections (2-5µg/ml))
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-155-029
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Differential Regulation of Estrogen Receptor Subtypes alpha and beta in Human Aortic Smooth Muscle Cells by Oligonucleotides and Estradiol
:
F. Barchiesi, et al.; J. Clin. Endocrinol. Metab.
89
, 2373 (2004)
Abstract
;
Full Text
Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast:
R.K. Dubey, et al.; J. Clin. Endocrinol. Metab.
90
, 247 (2005)
Abstract
;
Full Text
Related Products
ALX-155-029
Blocking Peptide for PAb to Estrogen Receptor β (human) (Prod. No.
ALX-210-180
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-131
Revised 19-Nov-07
Polyclonal Antibody to Glucocorticoid Receptor
SYNONYMS
anti-GR PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Glucocorticoids & Glucocorticoid Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-131-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
SOURCE/HOST:
From rabbit.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Lyophilized.
RECONSTITUTION:
Reconstitute with PBS.
IMMUNOGEN:
Synthetic peptide corresponding to aa 346-367 (D
346
QKPIFNVIPPIPVGSENWNRC
367
) of human GR (glucocorticoid receptor).
SPECIFICITY:
Recognizes all forms of human, mouse and rat GR. Detects a band of ~97kDa by Western blot. Does not interfere with receptor DNA binding.
APPLICATION:
Immunocytochemistry (1µg/ml)
Immunohistochemistry (paraffin sections)
Western Blot (5µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-157-015
.
Product Specific Literature References
Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors:
J.A. Cidlowski, et al.; Mol. Endocrinol.
4
, 1427 (1990)
Abstract
Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells:
J.E. Pawlowski, et al.; J. Biol. Chem.
277
, 20702 (2002)
Abstract
;
Full Text
Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells:
E.R. James, et al.; Invest. Ophthalmol. Vis. Sci.
44
, 5269 (2003)
Abstract
;
Full Text
Differential effects of adrenalectomy on melanin-concentrating hormone and orexin A:
D.L. Drazen, et al.; Endocrinology
145
, 3404 (2004)
Abstract
Related Products
ALX-157-015
Blocking Peptide for PAb to Glucocorticoid Receptor (Prod. No.
ALX-210-131
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-153
Revised 07-May-07
Polyclonal Antibody to Glucocorticoid Receptor
SYNONYMS
anti-GR PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Glucocorticoids & Glucocorticoid Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-153-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
SOURCE/HOST:
From rabbit.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Lyophilized.
RECONSTITUTION:
Reconstitute with PBS.
IMMUNOGEN:
Synthetic peptide corresponding to aa 245-259 (C
245
KPLILPDTKPKIKD
259
) of human GR (glucocorticoid receptor).
SPECIFICITY:
Recognizes human, mouse and rat GR. Detects a band of ~97kDa by Western blot. Does not interfere with receptor DNA binding.
APPLICATION:
Gel Shift Assays
Immunohistochemistry (frozen sections (1µg/ml))
Immunoprecipitation (5µg/m), Chromatin Immunoprecipitation
Western Blot (5µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-157-016
.
Product Specific Literature References
Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple forms in vitro and distinct localization of cytoplasmic and nuclear receptors:
J.A. Cidlowski, et al.; Mol. Endocrinol.
4
, 1427 (1990)
Abstract
Differential activity of progesterone and glucocorticoid receptors on mouse mammary tumor virus templates differing in chromatin structure:
C.L. Smith, et al.; J. Biol. Chem.
272
, 14227 (1997)
Abstract
;
Full Text
Related Products
ALX-157-016
Blocking Peptide for PAb to Glucocorticoid Receptor (Prod. No.
ALX-210-153
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-155
Revised 11-Nov-05
Polyclonal Antibody to Glucocorticoid Receptor
SYNONYMS
anti-GR PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Glucocorticoids & Glucocorticoid Receptors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-155-R200
200 µl
355.00 USD
