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SMRT & N-CoR / Related Products
You are here: Product Lines > DNA Regulation / Transcription > Transcription Regulators / Related Products > SMRT & N-CoR / Related Products
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ALX-210-253 Revised 12-Jul-07
Polyclonal Antibody to SMRT (human)
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SYNONYMS anti-Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor (human) PAb
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY SMRT & N-CoR / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-253-C100   100 µg 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Epitope-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 1302-1495 of human SMRT (silencing mediator of retinoic acid and thyroid hormone receptor).
SPECIFICITY: Recognizes human SMRT. Detects a band of ~250kDa by Western blot.
APPLICATION: Immunoprecipitation, Chromatin Immunoprecipitation
Western Blot (2µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
General Information
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. SMRT (silencing mediator of retinoic acid & thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-254 Revised 01-Feb-07
Polyclonal Antibody to N-CoR
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SYNONYMS anti-Nuclear Receptor Co-repressor PAb
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY SMRT & N-CoR / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-254-C050   50 µg 524.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.7mg/ml
PURITY DETAIL: Epitope-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 2437-2453 (CP2437APLLSAQYETLSDSDD2453) of mouse N-CoR (nuclear receptor co-repressor).
SPECIFICITY: Recognizes human and mouse N-CoR.
APPLICATION: Immunoprecipitation, Chromatin Immunoprecipitation
Western Blot (1µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-163-007.
General Information
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. SMRT (silencing mediator of retinoic acid & thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-285 Revised 30-Oct-06
Polyclonal Antibody to SMRT (human)
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SYNONYMS anti-Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor (human) PAb
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY SMRT & N-CoR / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-285-C100   100 µg 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
FORMULATION: Liquid. Epitope-affinity purified IgG in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Recombinant human SMRT (silencing mediator of retinoic acitd and thyroid hormone receptor) (aa 95-565).
SPECIFICITY: Recognizes human SMRT. Detects a band of ~250kDa by Western blot.
APPLICATION: Western Blot (4µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-804-281 Revised 11-Jul-08
Monoclonal Antibody to SMRT (human) (1212)
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SYNONYMS anti-Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor (human) MAb (1212)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY SMRT & N-CoR / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-281-C100   100 µg 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 1212
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 994-1005 (CGGA994SASDPHREKTQ1005) of human SMRT (silencing mediator of retinoic acid and thyroid hormone receptor).
SPECIFICITY: Recognizes human SMRT. Detects bands of ~250kDa and ~220kDa by Western blot corresponding to two known isoforms of SMRT. Does not cross-react with rat SMRT.
APPLICATION: Immunohistochemistry (1:50)
Western Blot (1:250)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-167-019.
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Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-282 Revised 06-Jan-05
Monoclonal Antibody to SMRT (human) (1542)
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SYNONYMS anti-Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor (human) MAb (1542)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY SMRT & N-CoR / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-282-C100   100 µg 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 1542
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. Purified antibody in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 994-1005 (A994SASDPHREKTQ1005) of human SMRT (silencing mediator of retinoic acid and thyroid hormone receptor).
SPECIFICITY: Recognizes human SMRT. Detects bands of ~250kDa and ~220kDa by Western blot corresponding to two known isoforms of SMRT.
APPLICATION: Immunohistochemistry
Western Blot (4µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-167-019.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
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