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ALX-803-043
Revised 11-Nov-05
Monoclonal Antibody to Progesterone Receptor (human) (phosphorylated) (pSer190) (1154)
SYNONYMS
anti-PR (human) (phosphorylated) (pSer
190
) MAb (1154)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Progesterone & Progesterone Receptor / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-803-043-C200
200 µg
420.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
1154
ISOTYPE:
Mouse IgG1
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 184-196 of human PR (progesterone receptor) phosphorylated at Ser
190
.
SPECIFICITY:
Recognizes phosphorylated human PR. Detects bands of ~115kDa (B-isoform) and ~90kDa (A-isoform) by Western blot.
APPLICATION:
Immunoprecipitation (10µg per sample)
Western Blot (4µg/ml)
Supershift (EMSA)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Specific Literature References
Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody:
D.L. Clemm, et al.; Mol. Endocrinol.
14
, 52 (2000)
Abstract
Further Categories Containing This Product:
Phospho-specific Antibodies
•
Monoclonal Antibodies
•
Tumor Markers
ALX-803-044
Revised 13-Jul-05
Monoclonal Antibody to Progesterone Receptor (human) (phosphorylated) (pSer294) (608)
SYNONYMS
anti-PR (human) (phosphorylated) (pSer
294
) MAb (608)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Progesterone & Progesterone Receptor / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-803-044-C200
200 µg
420.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
608
ISOTYPE:
Mouse IgG1
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic phosphopeptide corresponding to aa 287-300 of pSer
294
human PR (progesterone receptor).
SPECIFICITY:
Recognizes phosphorylated human PR. Detects a band of ~115kDa (B-isoform) by Western blot.
APPLICATION:
Immunoprecipitation (10µg/sample)
Western Blot (10µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Specific Literature References
Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody:
D.L. Clemm, et al.; Mol. Endocrinol.
14
, 52 (2000)
Abstract
Further Categories Containing This Product:
Phospho-specific Antibodies
•
Monoclonal Antibodies
•
Tumor Markers
ALX-803-007
Revised 09-Feb-07
Monoclonal Antibody to Progesterone Receptor (PR-AT 4.14)
SYNONYMS
anti-PR MAb (PR-AT 4.14)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Progesterone & Progesterone Receptor / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-803-007-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Others
CLONE:
PR-AT 4.14
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Ascites diluted in PBS containing 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 533-547(G
533
LPQVYPPYLNYLRP
547
) of N-terminal human PR (progesterone receptor) DNA binding domain.
SPECIFICITY:
Recognizes both the A and B forms of human, mouse, rat, bovine, rabbit and monkey PR. Detects bands of 94kDa (A form) and 120kDa (B form) by Western blot. Does not cross-react with AR (androgen receptor), ER (estrogen receptor) or GR (glucocorticoid receptor).
APPLICATION:
Immunohistochemistry (frozen sections, paraffin sections (5µg/ml)
Immunoprecipitation
Western Blot (5µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-027
.
Further Categories Containing This Product:
Monoclonal Antibodies
•
Tumor Markers
ALX-804-442
Revised 04-Aug-08
Monoclonal Antibody to Retinoic Acid Receptor α (human) (763)
SYNONYMS
anti-RARα MAb (763)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Retinoic Acid Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-804-442-C100
100 µg
390.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
763
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4, containing 0.2% BSA and 15mM sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 10-25 of human RARα (retinoic acid receptor-α).
SPECIFICITY:
Recognizes human RARα. Detects a band of ~60kDa by Western blot. Does not cross-react with human RARβ, RARγ or human retinoid X receptor (RXR).
APPLICATION:
Immunohistochemistry (formalin-fixed frozen sections, paraffin sections)
Immunoprecipitation
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-102
Revised 05-Jun-08
Monoclonal Antibody to Retinoic Acid Receptor α (Rα10)
SYNONYMS
anti-RARα MAb (Rα
10)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Retinoic Acid Receptors / Related Products
Ordering Information
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ALX-804-102-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Monkey
CLONE:
Rα10
ISOTYPE:
Mouse IgG1
FORMULATION:
Lyophilized from ascites containing 0.05% sodium azide.
RECONSTITUTION:
Reconstitute with PBS.
IMMUNOGEN:
Synthetic peptide corresponding to C-terminal aa 444-462 (C
444
SPSLSPSSHRSSPATQSP
462
) of mouse RARα (retinoic acid receptor α).
SPECIFICITY:
Recognizes human, mouse, rat and monkey RARα. Detects a band of ~45kDa by Western blot. Does not cross-react with RARβ or RARγ.
APPLICATION:
Immunoprecipitation
Western Blot (1-2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-166-003
.
General Information
BACKGROUND/TECHNICAL INFORMATION
Due to the extremely low levels of RAR expressed in native tissues, it is recommended that sensitive detection systems, such as enhanced chemiluminescence, are used.
The apparent molecular weight of RARα from transfected COS cells is ~45kDa. In rat tissues, such as skin and testis, doublets in the ~50kDa area are seen. RARα has been identified with this antibody in human dermal and neonatal fibroblast cell lines, as well as mouse F9 and human SH-SY5Y cells; however, RARα from human leukocytes and HUT102 cells were not identified by Prod. No.
ALX-804-102
suggesting that there may be structural variation of RARα between some cell types.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-443
Revised 09-Nov-04
Monoclonal Antibody to Retinoic Acid Receptor β (human) (336)
SYNONYMS
anti-RARβ (human) MAb (336)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Retinoic Acid Receptors / Related Products
Ordering Information
Product Numbers:
Format:
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ALX-804-443-C100
100 µg
390.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
336
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Protein G pruified antibody in PBS, pH 7.4, containing 0.2% BSA and 15mM sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 11-25 of human RARβ (retinoic acid receptor β).
SPECIFICITY:
Recognizes human RARβ. Detects a band of ~60kDa by Western blot. Does not cross-react with human RARα, RARγ or human retinoid X receptor (RXR).
APPLICATION:
Immunohistochemistry (formalin-fixed frozen sections, paraffin sections)
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-103
Revised 13-Dec-04
Monoclonal Antibody to Retinoic Acid Receptor β (Rβ28)
SYNONYMS
anti-RARβ MAb (Rβ28)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Retinoic Acid Receptors / Related Products
Ordering Information
Product Numbers:
Format:
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Unit Price:
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ALX-804-103-C050
50 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE:
Rβ28
ISOTYPE:
Mouse IgG2a
FORMULATION:
50µg Lyophilized antibody containing 0.05% sodium azide.
RECONSTITUTION:
Reconstitute with 0.1ml of distilled water.
IMMUNOGEN:
Synthetic peptide corresponding to C-terminal aa 463-482(P
463
SVSPSSVENSGVSQSPLLQ
482
) of mouse RARβ (retinoic acid receptor β).
SPECIFICITY:
Recognizes human and mouse RARβ. Does not cross-react with RARγ.
APPLICATION:
Western Blot (1-2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-166-004
.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-104
Revised 03-Mar-05
Monoclonal Antibody to Retinoid X Receptor β (MOK13-17)
SYNONYMS
anti-RXRβ MAb (MOK13-17)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Retinoid X Receptor / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-804-104-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE:
MOK13-17
ISOTYPE:
Mouse IgG1
CONCENTRATION:
2mg/ml
FORMULATION:
Liquid. Ascites diluted in PBS containing 0.05% sodium azide.
IMMUNOGEN:
Recombinant human RXRβ
(
retinoid X receptor β).
SPECIFICITY:
Recognizes human and mouse RXRβ. Detects a band of ~50kDa by Western blot. Does not cross-react with RXRα
or RXRg
.
APPLICATION:
Gel Super Shift Assays
Immunocytochemistry
Immunoprecipitation
Western Blot (5µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
H-2RIIBP expressed from baculovirus vector binds to multiple hormone response elements:
M.S. Marks, et al.; Mol. Endocrinol.
6
, 219 (1992)
Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION
Immunocytochemical staining of RXRβ in MCF-7 cells overexpressing RXRβ with Prod. No.
ALX-804-104
results in strong nuclear staining.
Gel super shift experiments show disruption of vitamin D receptor (VDR)/RXRβ/VDRE (DNA) complex formation when RXRβ was preincubated with Prod. No.
ALX-804-104
, yet experiments using THR showed a supershift of the thyroid hormone receptor (THR)/RXRβ heterodimer by this product.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-444
Revised 09-Nov-04
Monoclonal Antibody to Retinoid X Receptor γ (human) (1373)
SYNONYMS
anti-RXRγ (human) MAb (1373)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Retinoid X Receptor / Related Products
Ordering Information
Product Numbers:
Format:
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Unit Price:
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ALX-804-444-C100
100 µg
390.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
1373
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Protein G purified antibody in PBS, pH 7.4, containing 0.2% BSA and 15mM sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 213-226 of human RXRγ (retinoid X receptor γ).
SPECIFICITY:
Recognizes human RXRγ. Detects a band of ~60kDa by Western blot. Does not cross-react with human RXRα, RXRβ or human retinoic acid receptor (RAR).
APPLICATION:
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-644
Revised 29-May-07
Monoclonal Antibody to RORα (human) (6E8)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Nuclear Receptors Other Products
Ordering Information
Product Numbers:
Format:
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ALX-804-644-C050
50 µg
180.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
6E8
ISOTYPE:
Mouse IgG1
CONCENTRATION:
~580µg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.6. Contains no preservatives.
IMMUNOGEN:
Recombinant human RORα.
SPECIFICITY:
Recognizes human RORα1-4. The epitope is located at aa 84-105 of RORα4.
APPLICATION:
Electrophoretic Mobility Shift Assay (EMSA)
Immunoprecipitation
Western Blot (2µg/ml)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
USE/STABILITY:
Stable for 12 months after receipt when stored at +4°C.
HANDLING:
Do not freeze.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Intracellular localization of RORalpha is isoform and cell line-dependent:
A. Aschrafi, et al.; Biochim. Biophys. Acta
1763
, 805 (2006)
Abstract
Overexpression, refolding, and purification of polyhistidine-tagged human retinoic acid related orphan receptor RORalpha4:
A. Lechtken, et al.; Protein Expr. Purif.
49
, 114 (2006)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-804-589
Revised 11-Jul-08
Monoclonal Antibody to SHP (human) (SH2G5-C)
SYNONYMS
anti-Small Heterodimer Partner (human) MAb (SH2G5-C)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Nuclear Receptors Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-589-C050
50 µg
220.00 USD
ALX-804-589-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
SH2G5-C
ISOTYPE:
Rat IgG2aκ
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Purified IgG.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant human SHP (small heterodimer partner).
SPECIFICITY:
Recognizes human SHP.
APPLICATION:
ELISA
(direct and indirect: 1:2’000-1:10’000)
Western Blot
(1:2’000-1:5’000 using ECL)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-191
Revised 05-May-08
Monoclonal Antibody to SRC-1 (1135/H4)
SYNONYMS
anti-Steroid Receptor Coactivator-1 MAb (1135/H4)
anti-NCOA1 MAb (1135/H4)
anti-Nuclear Receptor Coactivator 1 MAb (1135/H4)
PRODUCT LINE
