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Innate Immunity Other Products
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ALX-804-134 Revised 01-Mar-07
Monoclonal Antibody to Bcl-10 (Carmen-1)
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SYNONYMS anti-CARMEN MAb (Carmen-1)
anti-CIPER MAb (Carmen-1)
anti-CLAP MAb (Carmen-1)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Caspase Recruitment Domain [CARD] Proteins / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-134-C100   100 µg 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE: Carmen-1
ISOTYPE: Rat IgM
SOURCE/HOST: Purified from concentrated hybridoma cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: >95% (SDS-PAGE)
PURITY DETAIL: Purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human Bcl-10.
SPECIFICITY: Recognizes human and mouse Bcl-10.
APPLICATION: Western Blot
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
USE/STABILITY:

Stable for at least 6 months after receipt when stored undiluted at +4°C.

HANDLING: Do not freeze/thaw.
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General Information
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
NF-kB Pathway Other ProductsInnate Immunity Other ProductsMonoclonal Antibodies
 
 
ALX-804-480 Revised 09-May-07
Monoclonal Antibody to Syk (SYK-01)
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PRODUCT LINE Immunology
PRODUCT CATEGORY Kinases in T Cell Signal Transduction / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-480-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE: SYK-01
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein A-affinity purified.
FORMULATION: Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN: Recombinant fragment (aa 5-360) of human Syk.
SPECIFICITY: Recognizes human, mouse and rat Syk.
APPLICATION: Immunocytochemistry
Immunoprecipitation
Western Blot
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fc epsilon receptors: M. Amoui, et al.; Eur. J. Immunol. 27, 321 (1997) Abstract
Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells: P. Tolar, et al.; Eur. J. Immunol. 27, 3389 (1997) Abstract
Requirement for a negative charge at threonine 60 of the FcRgamma for complete activation of Syk: P.G. Swann, et al.; J. Biol. Chem. 274, 23068 (1999) Abstract; Full Text
The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH(2)-terminal kinase 1: R. Arudchandran, et al.; J. Exp. Med. 191, 47 (2000) Abstract; Full Text
Vav1 regulates phospholipase cgamma activation and calcium responses in mast cells: T.S. Manetz, et al.; Mol. Cell. Biol. 21, 3763 (2001) Abstract; Full Text
Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation: M. Kovarova, et al.; Mol. Cell. Biol. 21, 8318 (2001) Abstract; Full Text
A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor: I. Halova, et al.; Int. Immunol. 14, 213 (2002) Abstract
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation: V. Parravicini, et al.; Nat. Immunol. 3, 741 (2002) Abstract
Further Categories Containing This Product:
Innate Immunity Other ProductsMonoclonal Antibodies
 
 
ALX-804-866 Revised 05-May-08
Monoclonal Antibody to ZBP1 (mouse) (Zippy-2)
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SYNONYMS anti-Z-DNA-binding Protein 1 (mouse) MAb (Zippy-2)
anti-Tumor Stroma And Activated Macrophage Protein DLM-1 (mouse) MAb (Zippy-2)
anti-DAI (mouse) MAb (Zippy-2)
anti-DNA-dependent Activator of IFN-regulatory Factors (mouse) MAb (Zippy-2)
PRODUCT LINE Immunology
PRODUCT CATEGORY Innate Immunity Other Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-866-C100   100 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: Zippy-2
ISOTYPE: Mouse IgG2a
SOURCE/HOST: Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant mouse ZBP1 (aa 1-411)
SPECIFICITY: Recognizes mouse ZBP1.
APPLICATION: Immunoprecipitation (1:200)
Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
MANUFACTURER Manufactured by Apotech Corporation.
 
 
ALX-804-865 Revised 13-May-08
Monoclonal Antibody to ZBP1 (Zippy-1)
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SYNONYMS anti-Z-DNA-binding Protein 1 MAb (Zippy-1)
anti-Tumor Stroma And Activated Macrophage Protein DLM-1 MAb (Zippy-1)
anti-DAI MAb (Zippy-1)
anti-DNA-dependent Activator of IFN-regulatory Factors MAb (Zippy-1)
PRODUCT LINE Immunology
PRODUCT CATEGORY Innate Immunity Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-865-C100   100 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE: Zippy-1
ISOTYPE: Mouse IgG2a
SOURCE/HOST: Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION: 0.5mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant mouse ZBP1 (aa 1-411)
SPECIFICITY: Recognizes human and mouse ZBP1.
APPLICATION: Immunoprecipitation (1:200)
Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER Manufactured by Apotech Corporation.
 
 
ALX-210-959 Revised 28-Apr-08
Polyclonal Antibody to ZBP1 (human) (AT133)
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SYNONYMS anti-Z-DNA-binding Protein 1 (human) PAb (AT133)
anti-Tumor Stroma And Activated Macrophage Protein DLM-1 (human) PAb (AT133)
anti-DAI (human) PAb (AT133)
anti-DNA-dependent Activator of IFN-regulatory Factors (human) PAb (AT133)
PRODUCT LINE Immunology
PRODUCT CATEGORY Innate Immunity Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-959-C100   100 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml
PURITY DETAIL: Protein A-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human ZBP1 (aa1-429)
SPECIFICITY: Recognizes human ZBP1.
APPLICATION: Immunoprecipitation (1:200)
Western blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information

ZBP1  is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.

MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response: A. Takaoka, et al.; Nature 448, 501 (2007) Abstract
 
 
ALX-210-957 Revised 23-Apr-08
Polyclonal Antibody to ZBP1 (mouse) (AT132)
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SYNONYMS anti-Z-DNA-binding Protein 1 (mouse) PAb (AT132)
anti-Tumor Stroma And Activated Macrophage Protein DLM-1 (mouse) PAb (AT132)
anti-DAI (mouse) PAb (AT132)
anti-DNA-dependent Activator of IFN-regulatory Factors (mouse) PAb (AT132)
PRODUCT LINE Immunology
PRODUCT CATEGORY Innate Immunity Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-957-C100   100 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml
PURITY: Protein A-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant mouse ZBP1 (aa 1-411) fused to a N-terminal tag.
SPECIFICITY: Recognizes mouse ZBP1.
APPLICATION: Immunoprecipitation (1:200)
Western blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
General Information

ZBP1  is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.

MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response: A. Takaoka, et al.; Nature 448, 501 (2007) Abstract
 
 

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