• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
DNA Regulation / Transcription
You are here: Product Lines > DNA Regulation / Transcription
 
Toolbar - View Selection
 
 Items 280-300 of 696 Page 15 of 35 Select Page: << 11 12 13 14 15 16 17 18 19 20  >>  
ALX-802-022 Revised 01-Jul-08
Monoclonal Antibody to ART2.2 (mouse) (NIKA-102)
Add to Clipboard
SYNONYMS anti-ecto-ADP-ribosyltransferase 2.2 (mouse) MAb (NIKA-102)
anti-ART2b (mouse) MAb (NIKA-102)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-802-022-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: NIKA-102
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART2.2 (ecto-ADP-ribosyltransferase 2.2; ART2b).
SPECIFICITY: Recognizes mouse ART2.2.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
A new monoclonal antibody detects a developmentally regulated mouse ecto-ADP-ribosyltransferase on T cells: subset distribution, inbred strain variation, and modulation upon T cell activation: F. Koch-Nolte, et al.; J. Immunol. 163, 6014 (1999) Abstract; Full Text
Metalloprotease-mediated shedding of enzymatically active mouse ecto-ADP-ribosyltransferase ART2.2 upon T cell activation: S. Kahl, et al.; J. Immunol. 165, 4463 (2000) Abstract; Full Text
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte, et al.; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-023 Revised 19-Oct-06
Monoclonal Antibody to ART3 (human) (GUGU3-A51)
Add to Clipboard
SYNONYMS anti-ecto-ADP-ribosyltransferase (human) MAb (GUGU3-A51)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-802-023-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: GUGU3-A51
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of human ART3 (ecto-ADP-ribosyltransferase 3).
SPECIFICITY: Recognizes human ART3.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005), (Review) Abstract
Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes: M. Friedrich, et al.; Asian J. Androl. 8, 281 (2006) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte, et al.; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-024 Revised 19-Oct-06
Monoclonal Antibody to ART3 (mouse) (GUGU3-A34)
Add to Clipboard
SYNONYMS anti-ecto-ADP-ribosyltransferase 3 (mouse) MAb (GUGU3-A34)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-802-024-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: GUGU3-A34
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART3 (ecto-ADP-ribosyltransferase 3).
SPECIFICITY: Recognizes mouse ART3.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005) Abstract
Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes: M. Friedrich, et al.; Asian J. Androl. 8, 281 (2006) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-025 Revised 01-Jul-08
Monoclonal Antibody to ART4 (human) (NONI-B4)
Add to Clipboard
SYNONYMS anti-ecto-ADP-ribosyltransferase 4 (human) MAb (NONI-B4)
anti-CD297 (human) MAb (NONI-B4)
anti-DO (human) MAb (NONI-B4)
anti-Dombrock Blood Group Carrier Molecule (human) MAb (NONI-B4)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-802-025-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: NONI-B4
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of human ART4 (ecto-ADP-ribosyltransferase 4; CD297).
SPECIFICITY: Recognizes human ART4.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte; Cell. Immunol. 236, 66 (2005) Abstract
A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens: I. Parusel, et al.; Cell Immunol. 236, 59 (2005) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
Complexities of the Dombrock blood group system revealed: M.E. Reid; Transfusion 45, 92S (2005) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-026 Revised 01-Jul-08
Monoclonal Antibody to ART4 (mouse) (GUGU4-A53)
Add to Clipboard
SYNONYMS anti-ecto-ADP-ribosyltransferase 4 (mouse) MAb (GUGU4-A53)
anti-CD297 (mouse) MAb (GUGU4-A53)
anti-DO (mouse) MAb (GUGU4-A53)
anti-Dombrock Blood Group Carrier Molecule (mouse) (GUGU4-A53)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-802-026-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: GUGU4-A53
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART4 (ecto-ADP-ribosyltransferase 4; CD297).
SPECIFICITY: Recognizes mouse ART4.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 1953, 22 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
Complexities of the Dombrock blood group system revealed: M.E. Reid; Transfusion 45, 92S (2005), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-421 Revised 26-Nov-04
Monoclonal Antibody to Aryl Hydrocarbon Receptor (RPT1)
Add to Clipboard
SYNONYMS anti-AhR MAb (RPT1)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Aryl Hydrocarbon Receptor/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-421-R100   100 µl 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE: RPT1
ISOTYPE: Mouse IgG1
FORMULATION: Liquid. Ascites containing 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 12-17 (R12KRRKP17) and aa 22-31 (V22KPIPAEGIK31) of mouse AhR (aryl hydrocarbon receptor).
SPECIFICITY: Recognizes human, mouse and rat AhR. Detects a band of ~95kDa by Western blot.
APPLICATION: Immunohistochemistry (paraffin sections)
Western Blot (1:1'000)
For immunoprecipitation, use MAb to AhR (RPT9) (Prod. No. ALX-804-423).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex: H.S. Chen & G.H. Perdew; J. Biol. Chem. 269, 27554 (1994) Abstract; Full Text
General Information
The aryl hydrocarbon receptor (AhR), also known as the dioxin receptor, is a ligand-activated helix/loop/helix transcription factor found in a variety of vertebrate species. The known ligands for AhR are foreign planar aromatic compounds, such as polycyclic aromatic compounds and halogenated aromatic compounds such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Unlike the steroid/thyroid hormone receptors, there is no known physiological ligand for the Ah Receptor.
Studies indicate that in non-ligand activated cells, AhR is found complexed with HSP90 predominantly in the cytoplasm. Upon binding to an agonist, the ligand-activated AhR is believed to transform to a nuclear, DNA binding form. This transformation process appears to involve dissociation of HSP90 from AhR followed by formation of a heterodimer with AhR nuclear translocator protein (Arnt). The AhR-ligand complex appears to initiate gene transcription of cytochrome P450 1A1.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-423 Revised 12-Jun-08
Monoclonal Antibody to Aryl Hydrocarbon Receptor (RPT9)
Add to Clipboard
SYNONYMS anti-AhR MAb (RPT9)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Aryl Hydrocarbon Receptor/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-423-R100   100 µl 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE: RPT9
ISOTYPE: Mouse IgG1
FORMULATION: Liquid. Ascites containing 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 12-17 (R12KRRKP17) and aa 22-31 (V22KPIPAEGIK31) of mouse AhR (aryl hydrocarbon receptor).
SPECIFICITY: Recognizes human, mouse and rat AhR. Detects a band of ~95kDa by Western blot.
APPLICATION:

Gel Shift Assay
Immunocytochemistry
Immunohistochemistry (paraffin sections (1:100); frozen sections)
Immunoprecipitation, Chromatin Immunoprecipitation (1:100)
Note: For Western blot use MAb to AhR (RPT1) (Prod. No. ALX-804-421).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-381 Revised 16-Jun-08
Monoclonal Antibody to ATF6 (70B1413.1)
Add to Clipboard
SYNONYMS anti-Activating Transcription Factor 6 MAb (70B1413.1)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Transcription Factors Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-381-C100   100 µg 293.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE: 70B1413.1
ISOTYPE: Mouse IgG1
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
IMMUNOGEN: Partial human ATF6 (activating transcription factor 6) containing aa 1-273.
SPECIFICITY: Recognizes human, mouse, rat, rabbit and hamster ATF6. Detects bands of ~90kDa (full length ATF6) and ~50-70kDa (cleaved forms of ATF6)  by Western blot.
APPLICATION: Immunocytochemistry (see [5] and [12])
Immunohistochemistry (paraffin sections, see [6], frozen sections, see [19])
Immunoprecipitation (see [3]) and ChIP (see [16] and [18])
Western Blot (1-5µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 6 months when stored at +4°C.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
[1] Requirement of the p38 mitogen-activated protein kinase signalling pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription factor 6 as a target for stress-i: S. Luo and A.S. Lee; Biochem. J. 366, 787 (2002) Abstract; Full Text
[2] Kaposi’s sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile: R.G. Jenner, et al.; PNAS 100, 10399 (2003) Abstract
[3] Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response: M. Hong, et al.; J. Biol. Chem. 279, 11354 (2004) Abstract; Full Text
[4] A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin: A.C. Nyborg, et al.; J. Biol. Chem. 279, 43148 (2004) Abstract; Full Text
[5] The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor: M. Thomas, et al.; J. Biol. Chem. 280, 21264 (2005) Abstract; Full Text
[6] Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease: B. van Kollenburg, et al.; J. Neuropathol. Exp. Neurol. 65, 707 (2006) Abstract
[7] Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus: B.L. Williams and W.I. Lipkin; J. Virol. 80, 8613 (2006) Abstract
[8] Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress: J.B. DuRose, et al.; Mol. Biol. Cell 17, 3095 (2006) Abstract; Full Text
[9] Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase: A.C. Nyborg, et al.; FASEB J. 20, 1671 (2006) Abstract
[10] Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system: A.J. Okumura, et al.; J. Biol. Chem. 281, 4495 (2006) Abstract; Full Text
[11] Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury: B. Bailly-Maitre, et al.; PNAS 103, 2809 (2006) Abstract; Full Text
[12] Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model: H. Kikuchi, et al.; PNAS 103, 6025 (2006) Abstract; Full Text
[13] Nitric oxide-induced endoplasmic reticulum stress activates the expression of cargo receptor proteins and alters the glycoprotein transport to the Golgi complex: M. Renna, et al.; Int. J. Biochem. Cell Biol. 38, 2040 (2006) Abstract
[14] Flavivirus infection activates the XBP1 pathway of the unfolded protein response to cope with endoplasmic reticulum stress: C.Y. Yu, et al.; J. Virol. 80, 11868 (2006) Abstract; Full Text
[15] 3,3’-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5: M. Abdelrahim, et al.; Carcinogenesis 27, 717 (2006) Abstract; Full Text
[16] Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promoters: G. Donati, et al.; Nucleic Acids Res. 34, 3116 (2006) Abstract; Full Text
[17] Acetaminophen induces ER dependent signaling in mouse liver: G. Nagy, et al.; Arch. Biochem. Biophys. 459, 273 (2007) Abstract
[18] Regulation of ERGIC-53 gene transcription in response to endoplasmic reticulum stress: M. Renna, et al.; J. Biol. Chem. 282, 22499 (2007) Abstract; Full Text
[19] Eif-2a protects brainstem motoneurons in a murine model of sleep apnea: Y. Zhu, et al.; J. Neurosci. 28, 2168 (2008) Abstract
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress • Monoclonal Antibodies
 
 
ALX-804-134 Revised 01-Mar-07
Monoclonal Antibody to Bcl-10 (Carmen-1)
Add to Clipboard
SYNONYMS anti-CARMEN MAb (Carmen-1)
anti-CIPER MAb (Carmen-1)
anti-CLAP MAb (Carmen-1)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Caspase Recruitment Domain [CARD] Proteins/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-134-C100   100 µg 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE: Carmen-1
ISOTYPE: Rat IgM
SOURCE/HOST: Purified from concentrated hybridoma cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: >95% (SDS-PAGE)
PURITY DETAIL: Purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human Bcl-10.
SPECIFICITY: Recognizes human and mouse Bcl-10.
APPLICATION: Western Blot
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
USE/STABILITY:

Stable for at least 6 months after receipt when stored undiluted at +4°C.
HANDLING: Do not freeze/thaw.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
NF-kB Pathway Other Products • Innate Immunity Other Products • Monoclonal Antibodies
 
 
ALX-804-847 Revised 19-Jun-08
Monoclonal Antibody to Cardif (human) (Adri-1)
Add to Clipboard
SYNONYMS anti-CARD Adapter Inducing Interferon-β (human) MAb (Adri-1)
anti-IPS-1 Cardif (human) MAb (Adri-1)
anti-Interferon-β Promoter Stimulator Protein 1 (human) MAb (Adri-1)
anti-MAVS (human) MAb (Adri-1)
anti-Mitochondrial Antiviral Signalling Protein (human) MAb (Adri-1)
anti-VISA (human) MAb (Adri-1)
anti-Virus-induced Signalling Adapter (human) MAb (Adri-1)
PRODUCT LINE Immunology
PRODUCT CATEGORY Antiviral Signalling/Related Products
Ordering Information
Pro