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ALX-158-001
Revised 28-Feb-06
Histone H1-7 Substrate
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-158-001-M001
1 mg
70.00 USD
ALX-158-001-M005
5 mg
280.00 USD
Product Specification
SEQUENCE:
H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH
FORMULA:
C
31
H
58
N
14
O
9
MW:
770.9
PURITY:
≥98%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Substrate for cAMP-dependent protein kinase (PKA). The peptide is derived from the phosphorylation site (Ser
38
) in calf thymus histone H1.
Product Specific Literature References
Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase:
A.H. Pomerantz, et al.; PNAS
74
, 4261 (1977)
Abstract
Further Categories Containing This Product:
PKA Substrates
•
Peptides
ALX-158-002
Revised 28-Feb-06
[Ala32]-Histone H2B (29-35)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-158-002-M001
1 mg
75.00 USD
ALX-158-002-M005
5 mg
300.00 USD
Product Specification
SEQUENCE:
H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH
FORMULA:
C
38
H
74
N
18
O
10
MW:
943.1
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Inhibitor of cGMP-dependent protein kinase, derived by a serine-to-alanine substitution at position 32 of histone H2B (29-35). For the corresponding unsubstituted histone fragment see Prod. No.
ALX-158-003
.
Product Specific Literature References
D.B. Glass & M.D. Miller; Fed. Proc.
39
, 867 (1980)
Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein kinases to synthetic peptide inhibitors:
D.B. Glass; Biochem. J.
213
, 159 (1983)
Abstract
Further Categories Containing This Product:
PKG Inhibitors
•
Peptides
ALX-158-003
Revised 04-Jul-03
Histone H2B (29-35)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-158-003-M001
1 mg
50.00 USD
ALX-158-003-M005
5 mg
200.00 USD
Product Specification
SEQUENCE:
H-Arg-Lys-Arg-Ser-Arg-Lys-Glu-OH
FORMULA:
C
38
H
74
N
18
O
11
MW:
959.1
PURITY:
≥97%
APPEARANCE:
White powder.
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Substrate for cGMP-dependent protein kinase corresponding to residues 29-35 of histone H2B. For the corresponding alanine-for-serine substituted peptides see Prod. No.
ALX-158-002
and Prod. No.
ALX-158-004
.
Product Specific Literature References
Comparison of the substrate specificity of adenosine 3':5'- monophosphate- and guanosine 3':5'-monophosphate-dependent protein kinases. Kinetic studies using synthetic peptides corresponding to phosphorylation sites in histone H2B:
D.B. Glass & E.G. Krebs; J. Biol. Chem.
254
, 9728 (1979)
Abstract
;
Full Text
Further Categories Containing This Product:
PKG Substrates
•
Guanylyl Cyclases, Guanosine Phosphate Metabolism / Related Products
•
Peptides
ALX-158-004
Revised 13-Jan-05
[Ala34]-Histone H2B (29-35)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-158-004-M001
1 mg
60.00 USD
ALX-158-004-M005
5 mg
240.00 USD
Product Specification
SEQUENCE:
H-Arg-Lys-Arg-Ser-Arg-Ala-Glu-OH
FORMULA:
C
35
H
67
N
17
O
11
MW:
902.0
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Substrate for cGMP-dependent protein kinase. For the corresponding unsubstituted histone fragment see Prod. No.
ALX-158-003
.
Product Specific Literature References
Phosphorylation by guanosine 3':5'-monophosphate-dependent protein kinase of synthetic peptide analogs of a site phosphorylated in histone H2B:
D.B. Glass & E.G. Krebs; J. Biol. Chem.
257
, 1196 (1982)
Abstract
;
Full Text
Further Categories Containing This Product:
PKG Substrates
•
Peptides
ALX-162-017
Revised 08-Jan-03
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKC Inhibitors
Ordering Information
Product Numbers:
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ALX-162-017-M001
1 mg
70.00 USD
ALX-162-017-M005
5 mg
280.00 USD
Product Specification
FORMULA:
C
42
H
82
N
12
O
8
MW:
883.2
PURITY:
≥96%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Effective inhibitor of protein kinase C (PKC)-catalyzed histone phosphorylation.
Product Specific Literature References
Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C:
C.G. Ioannides, et al.; Cell. Immunol.
131
, 242 (1990)
Abstract
N-myristyl-Lys-Arg-Thr-Leu-Arg: a novel protein kinase C inhibitor:
C.A. O'Brian, et al.; Biochem. Pharmacol.
39
, 49 (1990)
Abstract
Further Categories Containing This Product:
Histones / Related Products
•
Peptides
ALX-201-156
Revised 08-Dec-04
Histone H1.0 (human) (recombinant)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-156-M001
1 mg
170.00 USD
Product Specification
MW:
~21kDa.
SOURCE/HOST:
Produced in
E. coli.
PURITY:
≥98% (SDS-PAGE, HPLC)
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in 100% ethanol, methanol, DMSO or aqueous solutions.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-157
Revised 23-Feb-07
Histone H1.3 (human) (recombinant)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-201-157-M001
1 mg
170.00 USD
Product Specification
MW:
~22kDa.
SOURCE/HOST:
Produced in
E. coli.
PURITY:
≥95% (HPLC)
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in 100% ethanol, methanol, DMSO or aqueous solutions.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P16402:
Histone H1.3 (human)
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-159
Revised 08-Dec-04
Histone H1.5 (human) (recombinant)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-159-M001
1 mg
170.00 USD
Product Specification
MW:
~23kDa.
SOURCE/HOST:
Produced in
E. coli.
PURITY:
≥98% (SDS-PAGE, HPLC)
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in 100% ethanol, methanol, DMSO or aqueous solutions.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-160
Revised 08-Dec-04
Histone H1.2 (human) (recombinant)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-160-M001
1 mg
170.00 USD
Product Specification
MW:
~21kDa.
SOURCE/HOST:
Produced in
E. coli
.
PURITY:
≥98% (SDS-PAGE, HPLC)
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in 100% ethanol, methanol, DMSO or aqueous solutions.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-176
Revised 30-Sep-05
Histone γ-H2AX (human) (recombinant)
SYNONYMS
Histone H2AFX (human) (recombinant)
Histone H2A.X (human) (recombinant)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histones / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-176-M001
1 mg
290.00 USD
ALX-201-176-M005
5 mg
1'160.00 USD
Product Specification
SOURCE/HOST:
Produced in
E. coli
.
PURITY:
≥98% (SDS-PAGE; HPLC)
FORMULATION:
Lyophilized.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-279
Revised 18-Mar-08
CREB Binding Protein (mouse) (recombinant) (His)
SYNONYMS
CBP (mouse) (recombinant) (His)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
CREB & CREB Binding Protein / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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Add To Cart
ALX-201-279-C002
2 µg
280.00 USD
Product Specification
EC:
EC 2.3.1.48
SOURCE/HOST:
Produced in SF21 cells. Fused to a His-tag.
CONCENTRATION:
0.5mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol.
SPECIFIC ACTIVITY:
~50-100ng are required for standard HAT assay.
SHIPPING:
SHIPPED ON DRY ICE
SHORT TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store in liquid nitrogen.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link P45481:
CREB Binding Protein (mouse)
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
•
Histone Acetyl- & Methyl-Transferases / Related Products
ALX-201-280
Revised 18-Mar-08
GCN5 (human) (recombinant) (His)
SYNONYMS
GCN5L2 (human) (recombinant) (His)
Histone Acetyltransferase GCN5 (human) (recombinant) (His)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histone Acetyl- & Methyl-Transferases / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-280-C002
2 µg
280.00 USD
Product Specification
EC:
EC 2.3.1.48
SOURCE/HOST:
Produced in SF21 cells. Fused to a His-tag.
CONCENTRATION:
0.5mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol.
SPECIFIC ACTIVITY:
~200-300ng are required for standard HAT assay.
SHIPPING:
SHIPPED ON DRY ICE
SHORT TERM STORAGE:
-80°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store in liquid nitrogen.
General Information
BACKGROUND/TECHNICAL INFORMATION
Swiss-Prot link Q92830:
GCN5 (human)
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
ALX-201-281
Revised 13-Aug-08
PCAF (mouse) (recombinant) (His)
SYNONYMS
P300/CBP-associated Factor (mouse) (recombinant) (His)
Histone Acetyltransferase PCAF (mouse) (recombinant) (His)
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
Histone Acetyl- & Methyl-Transferases / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-201-281-C020
20 µg
280.00 USD
Product Specification
EC:
EC 2.3.1.48
SOURCE/HOST:
Produced in SF21 cells. Fused to a His-tag.
