ALEXIS Biochemicals: DR2313

ALX-270-452

Revised 27-Nov-06

DR2313
SYNONYMS	2-Methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidine-4-one
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	PARP Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-452-M001		1 mg	20.00 USD
ALX-270-452-M005		5 mg	60.00 USD
ALX-270-452-M025		25 mg	180.00 USD

Product Specification

FORMULA:	C₈H₁₀N₂OS
MW:	182.2
CAS NUMBER:	284028-90-6
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO, methanol or water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stock solutions are stable for up to 3 months when stored at -20°C.
HANDLING:	After reconstitution, prepare aliquots and store at -20°C. Protect from light.
HAZARD:	HARMFUL.

Product Description

Potent, water soluble competitive PARP inhibitor (IC₅₀=0.20µM and 0.24µM for PARP-1 and PARP-2 respectively).

Product Specific Literature References

A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats: H. Nakajima, et al.; Pharmacol. Exp. Ther. 312, 472 (2005) Abstract; Full Text

another CS2 website

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