ALEXIS Biochemicals: Daphnetin

ALX-270-281

Revised 28-Sep-06

Daphnetin
SYNONYMS	7,8-Dihydroxycoumarin
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	EGFR Kinase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-281-M005		5 mg	25.00 USD
ALX-270-281-M025		25 mg	95.00 USD

Product Specification

FORMULA:	C₉H₆O₄
MW:	178.1
CAS NUMBER:	486-35-1
RTECS:	GN6382600
PURITY:	≥97%
APPEARANCE:	White to rose powder.
SOLUBILITY:	Soluble in 100% ethanol, methanol or dimethyl formamide.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

Inhibitor of protein kinases. EGF receptor tyrosine kinase (IC₅₀=7.87µM), PKA (IC₅₀=9.33µM), PKC (IC₅₀=25.01µM). Antioxidant. Antimalarial agent.

Product Specific Literature References

Daphnetin: a novel antimalarial agent with in vitro and in vivo activity: Y.Z. Yang, et al.; Am. J. Trop. Med. Hyg. 46, 15 (1992) Abstract
Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor: E.B. Yang, et al.; BBRC 260, 682 (1999) Abstract

Further Categories Containing This Product:

Antioxidants, Flavonoids & Free Radical Scavengers Other Products • PKA Inhibitors • Malaria / Related Products • Tyrosine Kinase Inhibitors

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