ALEXIS Biochemicals: Decarestrictine D

ALX-380-133

Revised 20-Nov-08

Decarestrictine D
SYNONYMS	Tuckolide
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Other Natural Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-133-M001		1 mg	70.00 USD
ALX-380-133-M005		5 mg	280.00 USD

Product Specification

FORMULA:	C₁₀H₁₆O₅
MW:	216.2
CAS NUMBER:	127393-89-9, 141846-71-1
SOURCE/HOST:	Isolated from Penicillium sp.
PURITY:	≥98%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in methanol, acetone or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
IDENTITY:	Identity determined by ¹H-NMR.

Product Description

Shows hypolipidemic activity. Inhibitor of cholesterol biosynthesis.

Product Specific Literature References

Secondary metabolites by chemical screening. 8. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. I. Strain description, fermentation, isolation and properties: S. Grabley, et al.; J. Antibiot. 45, 56 (1992) Abstract
Secondary metabolites by chemical screening. 9. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. II. Structure elucidation of the decarestrictines A to D: A. Göhrt, et al.; J. Antibiot. 45, 66 (1992) Abstract
Chemical investigation of the metabolites from the Canadian tuckahoe, Polyporus tuberaster: W.A. Ayer, et al.; J. Nat. Prod. 55, 649 (1992) Abstract
A non-enzymatic reaction in the late biosynthesis of the decarestrictine family: M. Mayer & R. Thiericke; J. Antibiot. 46, 1372 (1993) Abstract
Synthesis of Tuckolide, a New Cholesterol Biosynthesis Inhibitor: M.B. Andrus & T.L. Shih; J. Org. Chem. 61, 8780 (1996) Abstract