ALEXIS Biochemicals: Deltamethrin

ALX-430-045

Revised 24-Feb-05

Deltamethrin
SYNONYMS	(S)-α-Cyano-(3-phenoxybenzyl (1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	PP2B [Calcineurin]/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-045-M010		10 mg	45.00 USD
ALX-430-045-M025		25 mg	96.00 USD

Product Specification

FORMULA:	C₂₂H₁₉Br₂NO₃
MW:	505.2
CAS NUMBER:	52918-63-5
MERCK INDEX:	14: 2883
PURITY:	≥98%
APPEARANCE:	Whitish film.
SOLUBILITY:	Soluble in DMSO, ethanol or acetone; insoluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HAZARD:	TOXIC.

Product Description

Type II pyrethrin, potent inhibitor of calcineurin (protein phosphatase 2B). Causes an increase in neurotransmitter release at synapses and also increases intrasynaptosomal Ca²⁺levels.

Product Specific Literature References

Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides: E. Enan & F. Matsumura; Biochem. Pharmacol. 43, 1777 (1992) Abstract
Nerve membrane Na+ channels as targets of insecticides: T. Narahashi; TIPS 13, 236 (1992), (Review) Abstract
Activation of phosphoinositide/protein kinase C pathway in rat brain tissue by pyrethroids: E. Enan & F. Matsumura; Biochem. Pharmacol. 45, 703 (1993) Abstract

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