ALEXIS Biochemicals: Limonin

ALX-350-225

Revised 29-Sep-08

Limonin
SYNONYMS	Limonoic acid di-δ-lactone
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Chemopreventive Agents

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-225-M050		50 mg	60.00 USD

Product Specification

FORMULA:	C₂₆H₃₀O₈
MW:	470.5
CAS NUMBER:	1180-71-8
MERCK INDEX:	14: 5494
SOURCE/HOST:	Isolated from grapefruit seed.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in 100% ethanol or glacial acetic acid; slightly soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

Bitter principle of citrus fruits. Inhibits chemically induced carcinogenesis. Inhibits HIV-1 replication. Shows antinociceptive effect. Does not possess any inherent antioxidant activity.

Product Specific Literature References

V.P. Maier, et al.; ACS Symposium Series 143, 63 (1980)
J.A. Klocke & I. Kubo; Ent. Exp. & Appl. 32, 299 (1982)
R.L. Rouseff; J. Agric. Food Chem. 30, 504 (1982)
M.A. Altieri, et al.; Protect. Ecol. 6, 91 (1984)
The effect of citrus limonoids on hamster buccal pouch carcinogenesis: E.G. Miller, et al.; Carcinogenesis 10, 1535 (1989) Abstract
L.K.T. Lam, et al.; ACS Symposium Series 546, 209 (1994)
Antinociceptive and anti-inflammatory activities of limonin isolated from the fruits of Evodia rutaecarpa var. bodinieri: H. Matsuda, et al.; Planta Med. 64, 339 (1998) Abstract
Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats: T. Tanaka, et al.; Biofactors 13, 213 (2000) Abstract
Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells: L. Battinelli, et al.; Planta Med. 69, 910 (2003) Abstract
Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside: A.P. Breksa, 3rd & G.D. Manners; J. Agric. Food Chem. 54, 3827 (2006) Abstract

Further Categories Containing This Product:

Natural Products - Antiviral / anti-HIV Agents • Natural Products for Neurological Research • Analgesic / Anti-nociceptive Agents / Related Products • Active Substances from Fruit and Vegetables

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