ALEXIS Biochemicals: Echinosporin

ALX-380-115

Revised 03-Apr-08

Echinosporin
SYNONYMS	NSC357683 XK 213
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antitumor Antibiotics

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-115-M001		1 mg	90.00 USD
ALX-380-115-M005		5 mg	360.00 USD

Product Specification

FORMULA:	C₁₀H₉NO₅
MW:	223.2
CAS NUMBER:	79127-35-8
RTECS:	JW5313000
SOURCE/HOST:	Isolated from Streptomyces sp.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in dimethyl formamide, methanol or water.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stock solutions are stable for at least 3 months when stored at -20°C.
HAZARD:	HARMFUL.

Product Description

Antitumor antibiotic. Inhibits cell cycle at the G(2)/M phase and induces apoptosis.

Product Specific Literature References

A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization: T. Sato, et al.; J. Antibiot. 35, 266 (1982) Abstract
Antitumor activity of echinosporin: M. Morimoto and R. Imai; J. Antibiot. 38, 490 (1985) Abstract
Approaches to the total synthesis of the antitumor antibiotic echinosporin: M. A. Kinsella; J. Org. Chem. 55, 105 (1990)
Applications of an asymmetric [2 + 2]-photocycloaddition. Total synthesis of (-)-echinosporin. Construction of an advanced 11-deoxyprostaglandin intermediate: A. B. Smith; JACS 114, 2567 (1992)
Biosynthesis of the antibiotic echinosporin by a novel branch of the shikimate pathway: A. Dubeler; Eur. J. Org. Chem. 2002, 983 (2002)
Echinosporins as new cell cycle inhibitors and apoptosis inducers from marine-derived Streptomyces albogriseolus: C.B. Cui, et al.; Fitoterapia 78, 238 (2007) Abstract

Further Categories Containing This Product:

Antibiotics - Apoptosis Inducers & Inhibitors • Antibiotics for Cell Cycle Research

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