ALEXIS Biochemicals: Conduritol B epoxide

ALX-270-082

Revised 28-Jan-05

Conduritol B epoxide
PRODUCT LINE	Obesity & Adipokines
PRODUCT CATEGORY	Glycosidases / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-082-M005		5 mg	35.00 USD
ALX-270-082-M025		25 mg	140.00 USD

Product Specification

FORMULA:	C₆H₁₀O₅
MW:	162.1
CAS NUMBER:	6090-95-5
PURITY:	≥97%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in water or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from moisture.

Product Description

Irreversible, high-potency inhibitor of various plant β-glucosidases and mammalian glucocerebrosidase. Used in vitro and animal models for study of Gaucher's disease.

Product Specific Literature References

[Mechanism of action of glycoside-splitting enzymes. V. Labelling of the active center of beta-glucosidases A and B from sweet almond emulsin with (3H)6-bromo-6-deoxyconduritol B epoxide]: G. Legler; Hoppe-Seyler's Z. Physiol. Chem. 351, 25 (1970) Abstract
The Gaucher mouse: differential action of conduritol B epoxide and reversibility of its effects: M.C. Stephens, et al.; J. Neurochem. 30, 1023 (1978) Abstract
Destruction and resynthesis of mouse beta-glucosidases: A. Hara & N.S. Radin; Biochim. Biophys. Acta 582, 412 (1979) Abstract
beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell: D.S. Newburg, et al.; Biochim. Biophys. Acta 877, 121 (1986) Abstract
Normalization of liver glucosylceramide levels in the "Gaucher" mouse by phosphatidylserine injection: S.C. Datta and N.S. Radin; BBRC 152, 155 (1988) Abstract

Further Categories Containing This Product:

Plant Research Reagents / Related Products

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