© 2008 Alexis Corporation
ALX-522-063 Revised 28-Aug-07
Adiponectin (human) (recombinant)
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SYNONYMS ACRP30 (human) (recombinant)
Adipocyte Complement Related Protein of 30kDa (human) (recombinant)
AdipoQ (human) (recombinant)
apM1 (human) (recombinant)
GBP28 (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Adiponectin [ACRP30]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-522-063-C050   50 µg 335.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
MW: ~33kDa (SDS-PAGE).
SOURCE/HOST: Produced in HEK 293 cells. Human adiponectin (aa 16-244) is fused at the N-terminus to a linker peptide (14 aa) and a FLAG®-tag.
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or other carrier protein.
BIOLOGICAL ACTIVITY: Activates AMPK.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
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Product Description
Mimics serum adiponectin by forming high molecular weight (HMW) and hexameric species.
Product Specific Literature References
Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase: A. Suzuki, et al.; Mol. Cell. Biol. 27, 4317 (2007) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q15848: Adiponectin (human) (precursor)

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism: A.H. Berg, et al.; Trends Endocrinol. Metab. 13, 84 (2002), (Review) Abstract
Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30): T.S. Tsao, et al.; J. Biol. Chem. 277, 29359 (2002) Abstract; Full Text
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity: U.B. Pajvani, et al.; J. Biol. Chem. 279, 12152 (2004) Abstract; Full Text
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
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