ALEXIS Biochemicals: Monoclonal Antibody to Granzyme B (human) (GrB7)

ALX-804-198

Revised 16-Mar-07

Monoclonal Antibody to Granzyme B (human) (GrB7)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Granzyme Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-198-C050		50 µg	630.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	GrB7
ISOTYPE:	Mouse IgG2a
QUANTITY:	1ml is sufficient for >200 tests.
CONCENTRATION:	~50µg/ml
FORMULATION:	Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.
IMMUNOGEN:	Human granzyme B.
SPECIFICITY:	Recognizes human granzyme B. Detects a band of ~33kDa by Western blot. Does not cross-react with granzyme A.
APPLICATION:	Immunohistochemistry (paraffin sections (1:20), not recommended for frozen sections) Western Blot
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C

Product Specific Literature References

Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins: J.A. Kummer, et al.; J. Immunol. Meth. 163, 77 (1993) Abstract
Granzyme B-expressing peripheral T-cell lymphomas: neoplastic equivalents of activated cytotoxic T cells with preference for mucosa- associated lymphoid tissue localization: P.C. de Bruin, et al.; Blood 84, 3785 (1994) Abstract
Localization and identification of granzymes A and B-expressing cells in normal human lymphoid tissue and peripheral blood: J.A. Kummer, et al.; Clin. Exp. Immunol. 100, 164 (1995) Abstract
Analysis of major histocompatibility complex class I expression on Reed- Sternberg cells in relation to the cytotoxic T-cell response in Epstein- Barr virus-positive and -negative Hodgkin's disease: J.J. Oudejans, et al.; Blood 87, 3844 (1996) Abstract
Granzyme B expression in Reed-Sternberg cells of Hodgkin's disease: J.J. Oudejans, et al.; Am. J. Pathol. 148, 233 (1996) Abstract

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Monoclonal Antibodies

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