ALEXIS Biochemicals: Polyclonal Antibody to 53BP1

ALX-210-419

Revised 30-Oct-06

Polyclonal Antibody to 53BP1
SYNONYMS	anti-Tumor Protein p53 Binding Protein 1 PAb anti-TP53BP1 PAb anti-p202 PAb
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	p53 Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-419-R050		50 µl	180.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. Neat serum containing 0.05% sodium azide.
IMMUNOGEN:	Recombinant human 53BP1 (tumor protein p53 binding protein 1) (aa 1308-1824).
SPECIFICITY:	Recognizes native and denatured forms of full-length human 53BP1. Cross-reacts with mouse 53BP1.
APPLICATION:	Immunocytochemistry (1:200); Immunoprecipitation; Western blot (1:2'000).
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
USE/STABILITY:	Storage at +4°C is recommended; if freezing is prefered add 50% glycerol.

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Product Description

The 53BP1 protein is implicated in the early response to DNA damage. The residues aa 1308-1824 are central to the antigen sequence recognized by the antibody ALX-210-419.

Product Specific Literature References

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage: L. Anderson, et al.; Mol. Cell. Biol. 21, 1719 (2001) Abstract
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis: D. Jullien, et al.; J. Cell Sci. 115, 71 (2002) Abstract; Full Text

Further Categories Containing This Product:

DNA Damage Checkpoint Other Products • Polyclonal Antibodies

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