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ALX-270-322 Revised 27-Nov-08
PD 168,393
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SYNONYMS 4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY EGFR Kinase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-322-M001   1 mg 156.00 USD Add To Cart
Product Specification
FORMULA: C17H13BrN4O
MW: 369.2
PURITY: ≥95%
APPEARANCE: Yellow to orange solid.
SOLUBILITY: Soluble in DMSO (200 mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Keep under inert gas. Protect from light.

Product Description
Potent, cell permeable, irreversible, and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50=700pM). Antitumor agent in vivo.
Product Specific Literature References
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor: D.W. Fry, et al.; PNAS 95, 12022 (1998) Abstract; Full Text
Further Categories Containing This Product:
Tyrosine Kinase Inhibitors • Antitumor Agents (Enzyme Inhibitors)
 
 
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