© 2008 Alexis Corporation
ALX-430-146
Revised 30-Nov-06
PAC-1
SYNONYMS
4-(Phenylmethyl)[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide-1-piperazine acetic acid
PRODUCT LINE
Cancer
PRODUCT CATEGORY
Antitumor Agents (Apoptosis Inducers)
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-430-146-M010
10 mg
45.00 USD
ALX-430-146-M050
50 mg
180.00 USD
Product Specification
FORMULA:
C
23
H
28
N
4
O
2
MW:
392.5
CAS NUMBER:
315183-21-2
PURITY:
≥98% (HPLC)
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in acetonitrile, DMSO, dioxane or methanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
First molecule to directly activate procaspase-3 to caspase-3
in vitro
. Has been shown to induce apoptosis in cancer cells.
Product Specific Literature References
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy:
K.S. Putt, et al.; Nat. Chem. Biol.
2
, 543 (2006)
Abstract
Further Categories Containing This Product:
Caspases Other Products
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