ALEXIS Biochemicals: Cinnamtannin B-1

ALX-350-365

Revised 11-Feb-08

Cinnamtannin B-1
SYNONYMS	Epicatechin-(4β→8,2β→O→7)-epicatechin-(4α→8)-epicatechin
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Apoptosis Inducers & Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-365-M005		5 mg	230.00 USD

Product Specification

FORMULA:	C₄₅H₃₆O₁₈
MW:	864.7
CAS NUMBER:	88082-60-4
SOURCE/HOST:	Isolated from Laurus nobilis L.
PURITY:	≥90% (¹H-NMR)
APPEARANCE:	Brown solid.
SOLUBILITY:	Soluble in 100% ethanol, methanol or in a mixture of DMSO and water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light. Keep under inert gas.

Product Description

A-type proanthocyanidin contained in several plant species such as Laurus nobilis L., Vaccinium vitis-idaea, Parameria laevigata, Cinnamomum zeylanicum and Lindera umbellata. Has potent antioxidant activity. Protective agent against oxidative stress and apoptosis in human platelets. Reduces hyperaggregability in platelets from type 2 diabetic patients.

Product Specific Literature References

Pharmacological Studies on Linderae umbellatae Ramus, IV*. Effects of condensed tannin related compounds on peptic activity and stress-induced gastric lesions in mice: N. Ezaki, et al.; Planta Med. 51, 34 (1985) Abstract
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents: Y. Kashiwada, et al.; J. Nat. Prod. 55, 1033 (1992) Abstract
Antioxidant activity of tannin components from Vaccinium vitis-idaea L: K.Y. Ho, et al.; J. Pharm. Pharmacol. 51, 1075 (1999) Abstract
Studies on the constituents of bark of Parameria laevigata Moldenke: K. Kamiya, et al.; Chem. Pharm. Bull. 49, 551 (2001) Abstract; Full Text
Cinnamtannin B1 activity on adipocytes formation: M. Taher, et al.; Med. J. Malaysia 59, 97 (2004) Abstract
Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity: G.K. Jayaprakasha, et al.; J. Agric. Food Chem. 54, 1672 (2006) Abstract
Characterization of the intracellular mechanisms involved in the antiaggregant properties of cinnamtannin B-1 from bay wood in human platelets: N. Ben Amor, et al.; J. Med. Chem. 50, 3937 (2007) Abstract
Cinnamtannin B-1 from bay wood exhibits antiapoptotic effects in human platelets: A. Bouaziz, et al.; Apoptosis 12, 489 (2007) Abstract
Cinnamtannin B-1 from bay wood reduces abnormal intracellular Ca2+ homeostasis and platelet hyperaggregability in type 2 diabetes mellitus patients: A. Bouaziz, et al.; Arch. Biochem. Biophys. 457, 235 (2007) Abstract

Further Categories Containing This Product:

Active Substances from Fruit and Vegetables • Natural Products - Antioxidants • Flavonoids / Related Products

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