© 2008 Alexis Corporation
ALX-260-078
Revised 17-Jan-06
Ac-DMQD-AMC
SYNONYMS
Caspase-3 Substrate (Fluorogenic)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Caspase Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-260-078-M001
1 mg
42.00 USD
ALX-260-078-M005
5 mg
163.00 USD
Product Specification
SEQUENCE:
Ac-Asp-Met-Gln-Asp-AMC (AMC=7-Amino-4-methylcoumarin)
FORMULA:
C
30
H
38
N
6
O
12
S
MW:
706.7
PEPTIDE CONTENT:
75-95%.
PURITY:
≥98% (HPLC)
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in DMSO. Dilute with distilled water or buffer. Also soluble in phosphate buffer, pH 7.5
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Keep cool and dry.
Product Description
Fluorogenic substrate for caspase-3.
Product Specific Literature References
Bid truncation, bid/bax targeting to the mitochondria, and caspase activation associated with neutrophil apoptosis are inhibited by granulocyte colony-stimulating factor
:
N.A. Maianski, et al.; J. Immunol.
172
, 7024 (2004)
Abstract
The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status
:
M. Kovarikova, et al.; Differentiation
72
, 23 (2004)
Abstract
Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells
:
J. Hofmanova; Eur. J. Nutrition
44
, 40 (2005)
Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION
AMC has an excitation maximum of 380nm and an emission maximum of 460nm.
© 2008 ALEXIS Corporation,
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