© 2008 Alexis Corporation
ALX-270-404
Revised 24-Jan-06
Cilostamide
SYNONYMS
N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
OCP 3689
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Phosphodiesterases / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-270-404-M005
5 mg
50.00 USD
ALX-270-404-M025
25 mg
200.00 USD
Product Specification
FORMULA:
C
20
H
26
N
2
O
3
MW:
342.4
CAS NUMBER:
68550-75-4
PURITY:
≥98%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light and oxygen. Packaged under inert gas.
Product Description
Selective inhibitor (IC
50
=70nM) of phosphodiesterase 3 (PDE3). Reverses the established effects of leptin on food intake and body weight. Blocks the leptin-induced tyrosine phosphorylation of STAT3 at the hypothalamic level.
General Literature References
A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding.
:
A.Z. Zhao, et al.; Nat. Neurosci.
5
, 727 (2002)
Abstract
Further Categories Containing This Product:
Obesity & Diabetes Other Products
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