© 2008 Alexis Corporation
ALX-270-397
Revised 09-Jan-08
Olomoucine, N9-Isopropyl-
SYNONYMS
6-Benzylamino-2-(2-hydroxyethylamino)-9-Isopropylpurine
PRODUCT LINE
Cell Cycle
PRODUCT CATEGORY
CDK & Cyclin Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-270-397-M001
1 mg
40.00 USD
ALX-270-397-M005
5 mg
120.00 USD
Product Specification
FORMULA:
C
17
H
22
N
6
O
MW:
326.4
CAS NUMBER:
158982-15-1
PURITY:
≥98% (HPLC)
APPEARANCE:
White to off-white crystalline solid.
SOLUBILITY:
Soluble in DMSO or dimethyl formamide; sparingly soluble in methanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stock solutions are stable for 3 months when stored at -20°C.
Product Description
Inhibitor of CDK1/cyclin B (IC
50
=2µM) and CDK5/p35 (IC
50
=3µM).
Product Specific Literature References
Inhibition of cyclin-dependent kinases by purine analogues
:
J. Vesely, et al.; Eur. J. Biochem.
224
, 771 (1994)
Abstract
Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis:
F.I. Raynaud, et al.; Mol. Cancer Ther.
3
, 353 (2004)
Abstract
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