ALEXIS Biochemicals: Monoclonal Antibody to Cyclin D1 (DCS-6)

ALX-804-001

Revised 22-Nov-07

Monoclonal Antibody to Cyclin D1 (DCS-6)
SYNONYMS	anti-Bcl-1 MAb (DCS-6) anti-PRAD-1 MAb (DCS-6)
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	CDK & Cyclin Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-001-C100		100 µg	270.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse Rat
CLONE:	DCS-6
ISOTYPE:	Mouse IgG2a
CONCENTRATION:	0.1mg/ml
FORMULATION:	Liquid. In 0.05M sodium phosphate buffer containing 0.2% gelatin and 0.1% sodium azide.
IMMUNOGEN:	Recombinant human cyclin D1.
SPECIFICITY:	Recognizes human, mouse and rat cyclin D1. Does not cross-react with cyclins D2 or D3.
APPLICATION:	Flow Cytometry (5µg/ml) Immunocytochemistry (5µg/ml) Immunohistochemistry (frozen sections, paraffin sections (5µg/ml) - pretreatment with pepsin or trypsin is required) Immunoprecipitation (see [3]) Western Blot (1µg/ml, see [3]) Functional Application: Neutralization studies (see [3])
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
HANDLING:	Do not freeze.

Product Specific Literature References

[1] Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining: C. Gillett, et al.; Cancer Res. 54, 1812 (1994) Abstract
[2] Cell cycle-related variation and tissue-restricted expression of human cyclin D1 protein: J. Bartkova, et al.; J. Pathol. 172, 237 (1994) Abstract
[3] Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines: J. Lukas, et al.; Oncogene 9, 707 (1994) Abstract

Further Categories Containing This Product:

Tumor Markers • Monoclonal Antibodies

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