© 2008 Alexis Corporation
ALX-340-062
Revised 18-Feb-08
Methyl Phytoprostane B1 (Type I) (racemic)
SYNONYMS
Methyl-8-(2-((E)-3-hydroxypent-1-enyl)-5-oxocyclopent-1-enyl)octanoate (racemic)
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
Eicosanoids Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-340-062-M005
5 mg
390.00 USD
Product Specification
FORMULA:
C
19
H
30
O
4
MW:
322.5
SOURCE/HOST:
Synthetic.
PURITY:
≥95% (
13
C-NMR)
APPEARANCE:
Colourless liquid.
SOLUBILITY:
Soluble in 100% ethanol, methanol, ether, ethyl acetate or halogenic solvents.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light and moisture.
HAZARD:
IRRITANT.
IDENTITY:
Determined by
1
H-NMR,
13
C-NMR and MS.
Product Description
Prostaglandin/jasmonate-like product of nonenzymatic lipid peroxidation. Occurs ubiquitously in healty plants and increases in response to oxidative stress. Could potentially be used as a marker of oxidative degradation of plant derived food. Powerful inducer of glutathione-S-transferase, jasmonic acid and other stress related responses. The role of phytoprostanes in human nutrition is not clarified yet, but they are associated with inhibition of dendritic cell interleukin-12 production and augmentation of TH2 cell polarization.
Product Specific Literature References
The isoprostanoid pathway in plants:
I. Thoma, et al.; Chem. Phys. Lipids
128
, 135 (2004)
Abstract
B1-phytoprostanes trigger plant defense and detoxification responses:
C. Loeffler, et al.; Plant Physiol.
137
, 328 (2005)
Abstract
A flexible synthesis of the phytoprostanes B1 type I and II:
S. El Fangour, et al.; J. Org. Chem.
70
, 989 (2005)
Abstract
Pollen-associated phytoprostanes inhibit dendritic cell interleukin-12 production and augment T helper type 2 cell polarization:
C. Traidl-Hoffmann, et al.; J. Exp. Med.
201
, 627 (2005)
Abstract
;
Full Text
Further Categories Containing This Product:
Plant Research Reagents / Related Products
•
Oxidative Stress Markers & Reagents / Related Products
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