© 2008 Alexis Corporation
ALX-350-342
Revised 02-Sep-08
Roquefortine C
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Neurotoxins
Ordering Information
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ALX-350-342-MC05
0.5 mg
320.00 USD
Product Specification
FORMULA:
C
22
H
23
N
5
O
2
MW:
389.5
CAS NUMBER:
58735-64-1
RTECS:
UQ4730500
SOURCE/HOST:
Isolated from MST-FP1764.
PURITY:
≥95% (HPLC)
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HAZARD:
TOXIC.
Product Description
Potent neurotoxin produced by a diverse range of fungi, most notably
Penicillium
species. Inhibits growth of Gram-positive bacteria. Inhibits cytochrome p450.
Product Specific Literature References
Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti:
S. Ohmomo, et al.; Agric. Biol. Chem.
39
, 1333 (1975)
Antimicrobial action of roquefortine:
B. Kopp-Holtwiesche and H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol.
10
, 41 (1990)
Abstract
Molecular requirements for inhibition of cytochrome p450 activities by roquefortine:
C. Aninat, et al.; Chem. Res. Toxicol.
14
, 1259 (2001)
Abstract
Inhibitory effects of roquefortine on hepatic cytochromes P450:
C. Aninat and M. Delaforge; Adv. Exp. Med. Biol.
500
, 331 (2001)
Abstract
The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes:
M. Keblys, et al.; Mycopathologia
158
, 317 (2004)
Abstract
Further Categories Containing This Product:
Mycotoxins
•
Cytochrome P450 [CYP450] / Related Products
•
Alkaloids
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