ALEXIS Biochemicals: Ac-YVAD-pNA

ALX-260-026

Revised 24-Feb-05

Ac-YVAD-pNA
SYNONYMS	Caspase-1 Substrate (Chromogenic)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-026-M001		1 mg	32.00 USD
ALX-260-026-M005		5 mg	68.00 USD

Product Specification

SEQUENCE:	Ac-Tyr-Val-Ala-Asp-pNA (pNA=p-Nitroaniline)
FORMULA:	C₂₉H₃₆N₆O₁₀
MW:	628.6
PEPTIDE CONTENT:	75-95%
PURITY:	≥99% (HPLC)
APPEARANCE:	White to off-white powder.
FORMULATION:	Lyophilized.
SOLUBILITY:	Soluble in DMSO. Dilute with buffer pH 7.5.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Keep cool and dry.

Product Description

Chromogenic substrate for caspase-1.

Product Specific Literature References

A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes: N.A. Thornberry, et al.; Nature 356, 768 (1992) Abstract
Peptidic p-nitroanilide substrates of interleukin-1 β-converting enzyme: L.A. Reiter; Int. J. Pept. Protein Res. 43, 87 (1994) Abstract
Interleukin-1 β converting enzyme: N.A. Thornberry; Meth. Enzymol. 244, 615 (1994) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

λmax of pNA is 400nm.

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