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ALX-850-310 Revised 04-Jul-08
M65® ELISA Kit
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PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Cytokeratin-based Apoptosis Detection
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-850-310-KI01 (CE Mark) 1 Kit Inquire
Product Specification
APPLICATION: For the specific and sensitive detection of soluble CK18 (cytokeratin 18). The M65® ELISA is primarily intended for quantitative determination of total cell death (apoptosis and necrosis) of CK18-positive cells (e.g. carcinoma) in human serum and plasma samples.
Use in combination with the M30-Apoptosense® ELISA Kit (Prod. No. ALX-850-270) to allow the calculation of apoptosis:necrosis ratios.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Do not freeze.
Product Specific Literature References
Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18: G. Kramer, et al.; Cancer Res. 64, 1751 (2004) Abstract
Determining tumor apoptosis and necrosis in patient serum using cytokeratin 18 as a biomarker: S. Linder, et al.; Cancer Lett. 214, 1 (2004) Abstract
Apoptosis pathway-targeted drugs--from the bench to the clinic: J. Cummings, et al; Biochim. Biophys. Acta 1705, 53 (2004) Abstract
Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis: H. Erdal, et al.; PNAS 102, 192 (2005) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Please also see our Product Flyer "M30 CytoDEATH™ - Key Marker to Detect Apoptosis in Epithelial Cells" (click here to download pdf) and the Original Manufacturer’s Product Description.
MANUFACTURER Manufactured by Peviva AB.
Related Products
Further Categories Containing This Product:
Tumor Markers • ELISA & EIA Kits
 
 
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