ALEXIS Biochemicals: Monoclonal Antibody to NS5B (HCV) (5B-3B1)

ALX-803-060

Revised 27-Apr-06

Monoclonal Antibody to NS5B (HCV) (5B-3B1)
SYNONYMS	anti-Nonstructural Protein 5B (HCV) MAb (5B-3B1)
PRODUCT LINE	Viral Signalling
PRODUCT CATEGORY	Hepatitis Viruses / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-803-060-R100		100 µl	360.00 USD

Product Specification

CLONE:	5B-3B1
ISOTYPE:	Mouse IgG2b
FORMULATION:	Liquid. Ascites fluid diluted in PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase.
SPECIFICITY:	Recognizes HCV NS5B (epitope mapped to NS5B aa 372-382).
APPLICATION:	Western Blot (1:1'000)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase: D. Moradpour, et al.; J. Biol. Chem. 277, 593 (2002) Abstract; Full Text
Hepatitis C virus RNA synthesis in a cell-free system isolated from replicon-containing hepatoma cells: R.W. Hardy, et al.; J. Virol. 77, 2029 (2003) Abstract; Full Text
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs: G. Randall, et al.; PNAS 100, 235 (2003) Abstract; Full Text
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids: S.B. Kapadia and F.V. Chisari; PNAS 102, 2561 (2005) Abstract; Full Text
Quantitative analysis of the hepatitis C virus replication complex: D. Quinkert, et al.; J. Virol. 79, 13594 (2005) Abstract
Complete translation of the hepatitis C virus genome in vitro: membranes play a critical role in the maturation of all virus proteins except for NS3: Y.V. Svitkin, et al.; J. Virol. 79, 6868 (2005) Abstract; Full Text

General Information

MANUFACTURER

Manufactured by Apotech Corporation

General Literature References

Unravelling hepatitis C virus replication from genome to function: B.D. Lindenbach and C.M. Rice; Nature 436, 933 (2005) Abstract