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ALX-201-294 Revised 06-Aug-08
SpvB (Salmonella enterica) (recombinant) (His)
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PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-294-C010   10 µg 270.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. Salmonella enterica SpvB is fused at the C-terminus to a His-tag.
CONCENTRATION: 0.5mg/ml
PURITY: ≥98%
PURITY DETAIL: Affinity purified
FORMULATION: Liquid. In PBS containing 50% glycerol.
APPLICATION: Functional application (1:10-1:100): ADP-ribosylation of cytoskeletal actin on R177
SHIPPING: SHIPPED ON DRY ICE
SHORT TERM STORAGE: -20°C
LONG TERM STORAGE: -80°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
The spvB gene-product of the Salmonella enterica virulence plasmid is a mono(ADP-ribosyl)transferase: H. Otto, et al.; Mol. Microbiol. 37, 1106 (2000) Abstract; Full Text
Salmonella enterica SpvB ADP-ribosylates actin at position arginine-177-characterization of the catalytic domain within the SpvB protein and a comparison to binary clostridial actin-ADP-ribosylating toxins: H. Hochmann, et al.; Biochemistry 45, 1271 (2006) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q4L1X7: SpvB (salmonella enterica)
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003) Abstract; Full Text
Targeting of the actin cytoskeleton during infection by Salmonella strains: D.G. Guiney & M. Lesnick; Clin. Immunol. 114, 248 (2005) Abstract
A steric antagonism of actin polymerization by a salmonella virulence protein: S.M. Margarit, et al.; Structure 14, 1219 (2006) Abstract
Related Products
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins • Actin / Related Products • Other Toxins
 
 
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