ALEXIS Biochemicals: ω-Conotoxin SVIB

ALX-630-053

Revised 14-Oct-08

ω-Conotoxin SVIB
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Neurotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-630-053-C500		500 µg	640.00 USD

Product Specification

SEQUENCE:	H-Cys-Lys-Leu-Lys-Gly-Gln-Ser-Cys-Arg-Lys-Thr-Ser-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Ser-Gly-Lys-Cys-NH₂ (Disulfide bonds between Cys¹-Cys¹⁶, Cys⁸-Cys²⁰and Cys¹⁵-Cys²⁶)
FORMULA:	C₁₀₅H₁₇₆N₃₈O₃₆S₆
MW:	2739.2
SOURCE/HOST:	Synthetic. Originally isolated from Conus striatus.
PURITY:	≥97%
APPEARANCE:	Lyophilized.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	VERY TOXIC.

Product Description

Neurotoxin. N-Type Ca²⁺channel blocker. Not for sale in U.S.A.

Product Specific Literature References

Conotoxins: B.M. Olivera, et al.; J. Biol. Chem. 266, 22067 (1991), (Minireview) Abstract; Full Text
Novel alpha- and omega-conotoxins from Conus striatus venom: C.A. Ramilo, et al.; Biochemistry 31, 9919 (1992) Abstract
Effects of diverse omega-conopeptides on the in vivo release of glutamic and gamma-aminobutyric acids: R. Newcomb & A. Palma; Brain Res. 638, 95 (1994) Abstract
Novel omega-conopeptides reduced field potential amplitudes in the rat hippocampal slice: J.A. Fox; Neurosci. Lett. 165, 157 (1994) Abstract
Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins: B.M. Olivera, et al.; Ann. Rev. Biochem. 63, 823 (1994), (Review) Abstract
A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202: K.J. Nielsen, et al.; J. Mol. Biol. 263, 297 (1996) Abstract

Further Categories Containing This Product:

Peptides • Ca2+ Channels (N-type) • Marine Natural Products

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