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ALX-280-018 Revised 14-Sep-07
Malonaldehyde bis(dimethyl acetal)
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SYNONYMS Malondialdehyde Precursor
MDA Precursor
1,1,3,3-Tetramethoxypropane
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Lipid Peroxidation
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-280-018-L005   5 ml 35.00 USD Add To Cart
Product Specification
FORMULA: C7H16O4
MW: 164.2
CAS NUMBER: 102-52-3
MERCK INDEX: 13: 5709 (Malondialdehyde (MDA))
PURITY: ≥98% (GLC)
APPEARANCE: Colorless liquid.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Keep away from heat, sources of ignition and incompatibles such as oxidizing agents.

Product Description
Precursor of malondialdehyde (MDA), a naturally occuring product of lipid peroxidation and prostaglandin biosynthesis, which is also formed by oxidation of polyunsaturated fatty acids in foods. Reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine.
Product Specific Literature References
[1] Malonaldehyde in aqueous solution and its role as a measure of lipid oxidation in foods: T. W. Kwon, et al.; J. Food Sci. 29, 294 (1964)
[2] Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes: H. Esterbauer, et al.; Free Radic. Biol. Med. 11, 81 (1991) Abstract
[3] Chemistry and biology of DNA damage by malondialdehyde: L.J. Marnett, et al.; IRAC Sci. Publ. 150, 17 (1999) Abstract
[4] Lipid peroxidation-DNA damage by malondialdehyde: L.J. Marnett, et al.; Mutat. Res. 424, 83 (1999) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Malondialdehyde (MDA) is very hygroscopic and can be stored only for a short time [1].
For biological experiments we recommend to use aqueous solutions of MDA freshly prepared by acid hydrolysis (1% H2SO4 at room temperature) of malonaldehyde bis(dimethyl acetal) (Prod. No. ALX-280-018) [2].
 
 
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