© 2008 Alexis Corporation
ALX-270-150 Revised 05-Oct-06
Vinpocetine
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SYNONYMS Eburnamenine-14-carboxylic acid-ethyl ester
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Phosphodiesterases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-150-M005   5 mg 30.00 USD Add To Cart
ALX-270-150-M025   25 mg 70.00 USD Add To Cart
Product Specification
FORMULA: C22H26N2O2
MW: 350.5
CAS NUMBER: 42971-09-5
MERCK INDEX: 14: 9991
RTECS: JW4792000
PURITY: ≥98%
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in DMSO, 100% ethanol or acetone.
SHIPPING: AMBIENT
LONG TERM STORAGE: +20°C
HAZARD: HARMFUL.

Product Description
Selective inhibitor of Ca2+/calmodulin-dependent phosphodiesterase 1 (PDE1).
Product Specific Literature References
Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle: M. Hagiwara, et al.; Biochem. Pharmacol. 33, 453 (1984) Abstract
Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta: H.S. Ahn, et al.; Biochem. Pharmacol. 38, 3331 (1989) Abstract
Regulation of cyclic AMP metabolism in bovine adrenal medullary cells: P.D. Marley & K.A. Thomsom; Biochem. Pharmacol. 44, 2105 (1992) Abstract
Cyclic 3',5'-nucleotide diesterases in dynamics of cAMP and cGMP in rat collecting duct cells: M. Yamaki, et al.; Am. J. Physiol. 262, F957 (1992) Abstract
Modulation of TNF alpha and IL-1 beta from endotoxin-stimulated monocytes by selective PDE isozyme inhibitors: K. Molnar-Kimber, et al.; Agents Actions 39, C77 (1993) Abstract