ALEXIS Biochemicals: N-Acetyl-eglin C (recombinant)

ALX-201-006

Revised 04-Sep-08

N-Acetyl-eglin C (recombinant)
PRODUCT LINE	Cancer
PRODUCT CATEGORY	Cathepsin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-201-006-MC01		0.1 mg	95.00 USD
ALX-201-006-MC05		0.5 mg	380.00 USD
ALX-201-006-M001		1 mg	670.00 USD

Product Specification

SEQUENCE:	Ac-Thr-Glu-Phe-Gly-Ser-Glu-Leu-Lys-Ser-Phe-Pro-Glu-Val-Val-Gly-Lys-Thr-Val-Asp-Gln-Ala-Arg-Glu-Tyr-Phe-Thr-Leu-His-Tyr-Pro-Gln-Tyr-Asn-Val-Tyr-Phe-Leu-Pro-Glu-Gly-Ser-Pro-Val-Thr-Leu-Asp-Leu-Arg-Tyr-Asp-Arg-Val-Arg-Val-Phe-Tyr-Asn-Pro-Gly-Thr-Asn-Val-Val-Asn-His-Val-Pro-His-Val-Gly-OH
FORMULA:	C₃₇₇H₅₅₂N₉₆O₁₀₇
MW:	8141.1
CAS NUMBER:	96380-69-7
SOURCE/HOST:	Produced in E. coli.
PURITY:	≥97% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in water.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C

Product Description

Eglin C was originally isolated from the leech Hirudo medicinalis [1]. Recombinant N-acetyl-eglin C is a 70 amino acid peptide with identical biological activity to native eglin C. An effective inhibitor of chymotrypsin and subtilisin as well as of leukocyte elastase and cathepsin G.

Product Specific Literature References

[1] Structure of the elastase-cathepsin G inhibitor of the leech Hirudo medicinalis: U. Seemüller, et al.; Hoppe-Seyler's Z. Physiol. Chem. 361, 1841 (1980) Abstract
[2] A large fragment approach to DNA synthesis: total synthesis of a gene for the protease inhibitor eglin c from the leech Hirudo medicinalis and its expression in E. coli: H. Rink, et al.; Nucl. Acids Res. 12, 6369 (1984) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link P01051: Eglin C (Hirudo medicinalis)

Further Categories Containing This Product:

Recombinant Proteins / Fusion Proteins • Proteases Other Products

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