ALEXIS Biochemicals: Ac-LEVD-AMC

ALX-260-083

Revised 17-Jan-06

Ac-LEVD-AMC
SYNONYMS	Caspase-4 Substrate (Fluorogenic)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-083-M001		1 mg	42.00 USD
ALX-260-083-M005		5 mg	163.00 USD

Product Specification

SEQUENCE:	Ac-Leu-Glu-Val-Asp-AMC (AMC=7-Amino-4-methylcoumarin)
FORMULA:	C₃₂H₄₃N₅O₁₁
MW:	673.7
PEPTIDE CONTENT:	75-95%
PURITY:	≥99% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in DMSO. Dilute with distilled water or buffer, pH 7.5.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Keep cool and dry.

Product Description

Fluorogenic substrate for caspase-4.

Product Specific Literature References

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis: N.A. Thornberry, et al.; J. Biol. Chem. 272, 17907 (1997) Abstract; Full Text

General Information

BACKGROUND/TECHNICAL INFORMATION

AMC has an excitation maximum of 380nm and an emission maximum of 460nm.

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