© 2008 Alexis Corporation
ALX-380-217
Revised 08-Apr-08
Reveromycin B
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Antibiotics for Cell Cycle Research
Ordering Information
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ALX-380-217-MC25
0.25 mg
320.00 USD
Product Specification
FORMULA:
C
36
H
52
O
11
MW:
660.8
CAS NUMBER:
144860-68-4
SOURCE/HOST:
Isolated from
Streptomyces
sp. MST-AS5344.
PURITY:
≥90% (HPLC)
APPEARANCE:
White to tan solid.
SOLUBILITY:
Soluble in ethyl acetate, 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Unstable in acidic conditions.
Product Description
Antibiotic. Much less active analog of reveromycin A (Prod. No.
ALX-380-216
), which is a G1 phase cell cycle inhibitor and induces apoptosis in osteoclasts. Useful negative control in resolving the mode of action of this class.
Product Specific Literature References
Reveromycins, new inhibitors of eukaryotic cell growth. I. Producing organism, fermentation, isolation and physico-chemical properties:
H. Takahashi, et al.; J. Antibiot. (Tokyo)
45
, 1409 (1992)
Abstract
Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities:
H. Takahashi, et al.; J. Antibiot. (Tokyo)
45
, 1414 (1992)
Abstract
Further Categories Containing This Product:
Antibiotics - Apoptosis Inducers & Inhibitors
•
Cell Cycle Blockers & Inhibitors/Related Products
•
Bone Metabolism Other Products
•
EGFR Kinase Inhibitors
•
Antibiotics - Antifungal
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