© 2008 Alexis Corporation
ALX-430-021
Revised 17-Jan-05
N-Acetyl-N-acetoxy-4-chlorobenzenesulphonamide
PRODUCT LINE
Nitric Oxide Pathway
PRODUCT CATEGORY
Nitric Oxide Pathway Other Products
Ordering Information
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ALX-430-021-M005
5 mg
40.00 USD
Product Specification
FORMULA:
C
10
H
10
ClNO
5
S
MW:
291.7
PURITY:
≥98%
APPEARANCE:
White crystals.
SOLUBILITY:
Soluble in DMSO or DMF; slightly soluble in methanol; not soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
Product Description
Nitroxyl (HNO) releasing compound in neutral solution. Release of nitric oxide was not detected. Potent vasorelaxant. Powerful inhibitor of aldehyde dehydrogenase.
Product Specific Literature References
Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase:
M.J.C. Lee, et al.; J. Med. Chem.
35
, 3648 (1992)
Abstract
N,O-diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties:
J.M. Fukuto, et al.; BBRC
187
, 1367 (1992)
Abstract
© 2008 ALEXIS Corporation,
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