ALEXIS Biochemicals: Amikacin . disulfate

ALX-380-266

Revised 03-Apr-08

Amikacin . disulfate
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-266-M250		250 mg	30.00 USD
ALX-380-266-G001		1 g	70.00 USD

Product Specification

FORMULA:	C₂₂H₄₃N₅O₁₃ . 2H₂SO₄
MW:	585.6 . 196.2
CAS NUMBER:	39831-55-5
MERCK INDEX:	14: 405
RTECS:	WK1961200
SOURCE/HOST:	Semisynthetic from kanamycin A (Prod. No. ALX-380-275).
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in water (50mg/ml).
ACTIVITY:	Potency is 647-786µg/ml (on dry basis).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Aminoglycoside antibiotic. Effective against Gram-negative and Gram-positive bacteria.

Product Specific Literature References

BB-K 8, a new semisynthetic aminoglycoside antibiotic: H. Kawaguchi, et al.; J. Antibiot. 25, 695 (1972) Abstract
Comparative pharmacokinetics of BB-K8 and kanamycin in dogs and humans: B.E. Cabana & J.G. Taggart; Antimicrob. Agents Chemother. 3, 478 (1973) Abstract
Comparative in vitro activity of three aminoglycosidic antibiotics: BB-K8, kanamycin, and gentamicin: P.K. Yu & J.A. Washington; Antimicrob. Agents Chemother. 4, 133 (1973) Abstract
Pharmacology of amikacin in humans: G.P. Bodey, et al.; Antimicrob. Agents Chemother. 5, 508 (1974) Abstract
Aminoglycoside antibiotics. VII. Acute toxicity of aminoglycoside antibiotics: K. Fujisawa, et al.; J. Antibiot. 27, 677 (1974) Abstract
Ototoxicity and pharmacokinetically determined dosages of amikacin in granulocytopenic cancer patients: F.J. Danhauer, et al.; Clin. Pharm. 1, 539 (1982) Abstract
Biological transformation of kanamycin A to amikacin (BBK-8): L.M. Cappelletti & R. Spagnoli; J. Antibiot. 36, 328 (1983) Abstract