© 2008 Alexis Corporation
ALX-163-011
Revised 14-Jul-08
NBD Peptide / NF-κB Blocker (cell permeable)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
NF-kB Pathway Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-163-011-1
1 Vial
240.00 USD
Product Specification
SEQUENCE:
GRKKRRQRRR-GG-TALDWSWLQTE-amide
FORMULA:
C
121
H
202
N
48
O
32
MW:
2841.2
QUANTITY:
50µl
CONCENTRATION:
10mM
PURITY:
≥95% (HPLC)
FORMULATION:
Liquid. In sterile PBS.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
-20°C
LONG TERM STORAGE:
-80°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Protect from moisture. Keep on ice at all times.
POSITIVE CONTROL:
Prod. No.
ALX-168-009/1
Product Description
For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter.
Product Specific Literature References
Selective inhibition of NF-kappaB blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo:
E. Jimi, et al.; Nature Med.
10
, 617 (2004)
Abstract
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex:
M.J. May, et al.; Science
289
, 1550 (2000)
Abstract
Characterization of the Ikappa B-kinase NEMO binding domain:
M.J. May, et al.; J. Biol. Chem.
277
, 45992 (2002)
Abstract
Related Products
ALX-168-009/1
L-TAT Control Peptide (for Prod. No.
ALX-159-600
)
Further Categories Containing This Product:
Peptides
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